National Science Council

National Health Research Institutes

Shan-hui Hsu

David Chen

Ing-Ming Chiu

Implantable nerve regeneration conduits and methods of making the same are disclosed. The implantable nerve regeneration conduits mainly comprise a biodegradable polymer and a metal. Moreover, the conduits may also comprise one or more nerve regeneration enhancing elements, which comprise bioactive molecules or cells. The inner surface of the conduits may be micropatterned photolithographic processes to form microgrooves for facilitating cell alignment.

Implantable nerve regeneration conduit

A novel biomedical material, which is characterized by coating a genetically engineered CBD-RGD peptide layer on the surface of a biomedical material consisting of PU to improve the attachment of tissue cells, such as fibroblasts, epithelial cells and endothelial cells. A modified artificial vessel is also disclosed, wherein the adherence of endothelial cells is enhanced by coating a genetically engineered CBD-RGD containing peptide layer on the inner surface of the artificial vessels pre-modified by cross-linked gelatin, and the adhering capacity and activation of platelets is reduced.

Growing community of inventors

Taichung, Taiwan

Shan-hui Hsu