Icecure Medical Ltd.

Shai Kaufman

Ron Hilleli

Naum Muchnik

Adir Weiser

Lior Lasker

Apparatus, including a probe, containing a first lumen and a second lumen and having a distal end that contacts tissue of a living subject. A fluid supply delivers a cryogenic fluid through the first lumen to the distal end and receives cryogenic fluid returning via the second lumen. A temperature sensor is located at the distal end. A pressure sensor located at a proximal end of the first lumen measures a pressure of the cryogenic fluid. A processor controls a delivery rate of the cryogenic fluid from the fluid supply, so that, when a temperature measured by the temperature sensor is less than a preset guard temperature, the delivery state is a preset low rate, and when the temperature measured by the temperature sensor is greater than or equal to the preset guard temperature, the delivery rate is set in response to a pressure measured by the pressure sensor.

Cryogen flow control

Cryogenic apparatus, consisting of a connector that has a connector base plate configured for connection to a conduit carrying a cryogen, and a slot extending across the base plate. The apparatus has a plug, which is configured for insertion into an opening in the base plate. The apparatus also has a latch plate that is configured to slide within the slot between a first position, in which the plug is inserted through an aperture in the latch plate into the opening, and a second position, in which a cryogenic probe is inserted through the aperture and brought into fluid communication with the opening. There is a sensor, which is coupled to control a flow of the cryogen through the conduit by detecting whether the latch plate is in the first position or the second position.

Cryogenic system connector

Apparatus, consisting of a probe, containing a lumen and having a distal end configured to contact tissue of a living subject. A temperature sensor is located at the distal end, and a pump, having a pump motor, is coupled to deliver a cryogenic fluid through the lumen to the distal end of the probe and to receive the cryogenic fluid returning from the probe. There is a separator, coupled to separate the returning cryogenic fluid into a returning cryogenic liquid and a returning cryogenic gas, and a flow meter, coupled to measure a rate of flow of the returning cryogenic gas. A processor is configured to control a rate of pumping of the pump motor in response to a temperature measured by the temperature sensor and the rate of flow of the returning cryogenic gas.

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Nir Eliyahu, Israel

Shai Kaufman