Steris Inc.

American Sterilizer Company

Shahin Shahin Keller

Sayed Sadiq Shah

Daniel A Klein

Nancy E Kaiser

Herb J Kaiser

Herbert J Kaiser

Kathleen M Antloga

Christopher C Heisig

Gurusamy Manivannan

Michael Ebers

Jason F Tirey

Mildred R Bernando

John Macauley

Gerald E Mcdonnell

A solvent blend cleaner useful for reflux cleaning of chemical manufacturing equipment, including that used in manufacturing pharmaceuticals, comprises a blend of environmentally friendly and safe solvents selected on the basis of specific criteria, such as vapor pressure, vapor density, boiling point, specific heat, and heat of vaporization, among other things; achieves excellent cleaning even upon further dilution with water; and avoids the disadvantages associated with the use of conventional commodity solvents in reflux cleaning methods. Desired solvency, cleaning and wetting properties of the inventive formulations in use can be achieved through blending of solvents having the selected criteria. Additives, such as surfactants, can be added to enhance cleaning and lower solvent requirements.

Environmentally friendly, multi-purpose refluxing cleaner

An aqueous, alkaline cleaning composition for use on hard-to-clean soils, encountered in pharmaceutical, personal care, food and cosmetic manufacturing, comprising a source of alkalinity, a biodegradable surfactant system further comprising one or more surfactants, one or more hydrotropes, and a UV-analyzable surfactant, and a biodegradable chelating agent. The composition offers unique advantages of stability over the expected shelf life, low-foaming property, phosphate-free and biodegradable components, and unexpectedly enhanced antimicrobial, including virucidal, activity in one cleaning composition. The UV-analyzable surfactant allows for validation of cleaning processes using known techniques for manufacturers who are required or desire to do so.

Biodegradable alkaline disinfectant cleaner with analyzable surfactant

A low pH disinfectant composition comprises an aqueous composition of a phenolic compound, an organic acid, and/or a dispersing surfactant and/or solvent. The disinfectant solution can be concentrated, or more preferably diluted ready to use, and is very effective in eradicating fungi including

Acidic phenolic disinfectant compositions

A cleaning composition includes a detectable substance which is relatively stable in the cleaning composition, for indicating whether the cleaning composition has been thoroughly removed from a vessel following a cleaning process. For pharmaceutical applications, the detectable substance is preferably a low-foaming surfactant that is detectable by high performance liquid chromatography at concentrations of around 10 ppm, or less. The surfactant is thus detectable in the same analytical procedure as are traces of pharmaceutical residues which have not been removed from the vessel. The analytical procedure is used to develop a cleaning protocol for future cleaning processes by determining the number of rinses needed for reducing the surfactant, and hence the cleaning product, and also the pharmaceutical residues, in the rinse water to predetermined acceptable levels.

Detection of residual cleaning product with analyzable surfactant

A method for treating medical instruments after a surgical procedure, which leaves blood or other body fluid on the instrument, includes applying a gel composition that inhibits the fluid from drying on the instruments. The gel composition is preferably a low viscosity gel exhibiting both sufficient flow and coating characteristics. The viscosity is preferably from about 700 to about 4,000 centipoise (cps), preferably around 3,000 cps. Applying a gel to post-surgical medical instruments contains and keeps protein containing fluids moist for extended periods of time and facilitates subsequent transportation, cleaning, and sterilization of such instruments.

Safe transport gel for treating medical instruments

Cleaning product with analyzable and stable surfactant

Growing community of inventors

Lexington Park, MD, United States of America

Shahin Shahin Keller