The United States of America, As Represented by the Secretary, Department of Health and Human Services

Merial Limited

Boehringer Ingelheim Animal Health USA Inc.

Shaden Kamhawi

Jesus G Valenzuela

Yasmine Belkaid

David Sacks

Laurent Bernard Fischer

Jose M C Ribeiro

Jose Ribeiro

Jean-Christophe Francis Audonnet

Jose M C Ribiero

Francis Milward

Jose Mc Ribeiro

The present invention provides vectors that contain and express in vivo or in vitro sand flysalivary antigens that elicit an immune response in animal or human against, vaccine compositions comprising said vectors and/orsalivary polypeptides, methods of vaccination against, and kits for use with such methods and compositions.

Leishmania vaccine using sand fly salivary immunogen

The present disclosure provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present disclosure also provides compositions for vaccines to prevent Leishmaniasis.

Anti-arthropod vector vaccines, methods of selecting and uses thereof

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The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.

Substantially purified salivaryandpolypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including theandpolynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating or preventingare disclosed.

Anti-arthropod vector vaccines method of selecting and uses thereof

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Rockville, MD, United States of America

Shaden Kamhawi