The First Affiliated Hospital of Sun Yat-sen University

National Supercomputer Centre in Guangzhou of Sun Yat-sen University

School of Data and Computer Sciences of Sun Yat-sen University

School of Data and Computer Science of Sun Yat-sen University

Sha Yu

Xi Zhang

Yutong Lu

Yao Lu

Qingtang Zhu

Jian Qi

Liwei Yan

Yunfei Du

Xiaolin Liu

Tao Lin

Shuang Zhu

Yongze Guo

The present invention relates to fields of clinical application of nerve defect repair and the medical three-dimensional (3D) printing technology, and provides an integrated visualization method for three-dimensional (3D) reconstruction of internal structure of human peripheral nerves. The method comprises the following steps: obtaining human peripheral nerves, preparing nerve specimens ex vivo by staining with an iodine preparation in combination with a freeze-drying method; scanning the pretreated peripheral nerves using Micro CT to acquire lossless two-dimensional images, and performing binarization processing to the two-dimensional images, then conducting image segmentation based on textural features to acquire images of nerve fascicles; finally, reconstructing the segmented images into a visualization model by using a supercomputer.

Integrated method for three-dimensional visualization reconstruction of the fascicular structure inside human peripheral nerves

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Guangdong, China

Sha Yu