Samsung Electronics Co., Ltd.

Seoul National University

Snu Rdb Foundation

Seungbeom Lee

Keongho Lee

Ho-Young Reho Lee

Jeong Hun Kim

Seungwook Lee

Jeonghun Kim

Young-Ger Suh

Sang Geon Kim

Kyu-Won Kim

Wonjin Kim

Joongbaik Kim

Chunmok Chung

Youngseh Kim

Youngger Suh

Hongchan An

Disclosed are a novel hypoxia-inducible factor 1α (HIF-1α) inhibitor, a method of preparing the same, and a pharmaceutical composition for preventing or treating an angiogenesis-related eye disease containing the same as an active ingredient. The compound of Example provided according to an embodiment of the present invention is capable of effectively inhibiting HIF-1α and is thus useful as a pharmaceutical composition for preventing or treating an angiogenesis-related eye disease.

HIF-1α inhibitor, preparation method therefor, and pharmaceutical composition for preventing or treating angiogenesis-associated eye disease, containing same as active ingredient

A data bus includes: a transaction selection circuit configured to receive vector data including a plurality of transactions from outside of the data bus, select at least one transaction from the plurality of transactions in which no traffic conflict occurs based on whether there is a traffic conflict among the plurality of transactions, and output the selected at least one transaction; and a memory data path including at least one register and configured to output the selected at least one transaction provided by the transaction selection circuit via the at least one register to the outside of the data bus.

Data bus, data processing method thereof, and data processing apparatus

A method for controlling a memory operation includes determining a number of commands for each memory address based on information of requests stored in an interface buffer and a scheduler buffer, determining a control state of the memory operation according to a command type with a largest number of commands, and determining types of a request transmitted to the scheduler buffer from the interface buffer and a request output from the scheduler buffer according to a control state of the memory operation. Other embodiments including an apparatus for controlling a memory are also disclosed.

Method and apparatus for controlling memory operation

A compound inhibiting Hsp90 and a pharmaceutical composition including the same as an active ingredient are described, which compound is represented by formula 2 and suppresses the expression of Hsp90, inhibits the accumulation of HIF-1&#x3b1;, the Hsp90 client protein, and efficiently inhibits the activation of VEGF. The compound displays low cytotoxicity and can be effectively used as an active ingredient of an anti-cancer agent, a diabetic retinopathy treating agent, and an anti-arthritic agent.

Compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient

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Seoul, South Korea

Seungbeom Lee