1st Biotherapeutics, Inc.

Seung Mook Lim

Jinhwa Lee

Jae Eun Kim

Suyeon Jo

Misoon Kim

A Yeong Park

Keonseung Lim

Hwajung Nam

Yejin Hwang

Yeonguk Jeon

Gadhe Changdev Gorakshnath

Minwoo Lee

Hyeongjun Kim

Wanjun Li

Gwibin Lee

Mingzhu Fan

Heekyoung Yang

Hyonam Kim

Gyooseung Jung

The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salts thereof, a composition comprising the compound, methods of using the compound for the treatment of various disorders associated with HPK1, and methods of preparing these compounds.

Substituted indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors

The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method to treat or prevent neurodegenerative diseases using the compound.

Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders

The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salts thereof, a composition comprising the compound, methods of using the compound for the treatment of various disorders associated with HPK1, and methods of preparing these compounds. 

Indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors and methods using same

The present disclosure provides a compound of Formula (I) or pharmaceutically acceptable salt, stereoisomers thereof, a pharmaceutical composition comprising the compound, and a method to treat or prevent neurodegenerative diseases using the compound. 

The present disclosure provides a compound of general Formula (I) having c-abl kinase inhibitory activity or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound, and a method useful to treat or prevent neurodegenerative diseases using the compound. 

Benzothiazol compounds and methods using the same for treating neurodegenerative disorders

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Gyeonggi-do, South Korea

Seung Mook Lim