Stemlab Inc.

Seung Kwon You

Jung Hyun Park

Min Ji Park

Won Jin Yun

Eun Kyoung Jun

Won-Jin Yun

Ji Hoon Jang

Byung Sun Yoon

Wei Wei Gao

Phil Jun Kang

Da-Ryeon Son

Jie Zheng

Won Jun Hong

Da Ryeon Son

In Yong Kim

Gyu Man Park

Ji Yong Park

Ji-Yong Park

Jang Bo Lee

A method for inducing reprogramming of neural stem cells from urine cells by introducing mRNAs of reprogramming factors Oct4, Sox2, Klf4, and Glis1 is disclosed. A composition for the prevention or treatment of neurological damage diseases with the neural stem cells induced by the method as an active ingredient is disclosed.

Method for direct reprogramming of urine cells into neural stem cells using synthetic MRNA

Provided is a method of inducing oligodendrocyte precursor cells (OPCs) through direct reprogramming from human somatic cells into which a nucleic acid molecule encoding an Oct4 protein or Oct4 protein-treated human somatic cells. The method of inducing OPCs by treating Oct4-overexpressing human somatic cells with a low molecular weight substance may establish OPCs with high efficiency in a short period of time through direct reprogramming without via neural stem cells, and thus the OPCs are useful as a cell therapeutic agent for an intractable demyelinating disease.

Method for inducing oligodendrocyte precursor cells from OCT4-induced human somatic cells through direct reprogramming

Method for inducing oligodendrocyte precursor cells from Oct4-induced human somatic cells through direct reprogramming

The present invention relates to a culture solution of MSCs derived from a fetus in amniotic fluid, and more specifically, to a composition for promoting hair growth or preventing hair loss, which includes a culture solution of MSCs overexpressing a reprogramming factor Nanog and derived from a fetus in amniotic fluid as an active ingredient. In addition, the present invention relates to a method for preparing the composition, which includes culturing Nanog-introduced MSCs derived from a fetus in amniotic fluid in a conditioned medium and collecting the culture solution. The conditioned medium composition according to the present invention exhibits a hair growth promoting effect, and thus is able to be used as cosmetic and pharmaceutical compositions for promoting hair growth.

Method for preparing composition for promoting hair growth using Nanog-introduced mesenchymal stem cells derived from fetus in amniotic fluid

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Yongin-si, South Korea

Seung Kwon You