Other

Snu Rdb Foundation

Industry-academic Cooperation Foundation, Dankook University

Seung Ki Lee

Jeong Hill Park

Man Ki Park

Jong Moon Kim

Sung Won Park

Jae Hyoung Park

Young Jong Kim

Byeong Moon Kim

Ju Yong Lee

Jin Ho Chung

Nak Doo Kim

Seung Ju Cho

Bok Deuk Kim

The present invention relates to a CDK-inhibiting pyrrolopyrimidine carboxamide derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating liver cell cancer. Compositions comprising a pyrrolopyrimidine carboxamide derivative of the present invention suppress the cell growth of SNU-354 cell, which is a liver cancer stem cell in humans, by inhibiting CDK1 and CDK2, and induces cell apoptosis of the cell by inhibiting CDK7 and CDK 7. Such compositions are useful for preventing or treating liver cell cancer.

CDK-inhibiting pyrrolopyrimidine carboxamide derivative or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing the same as active ingredient for preventing or treating hepatocellular carcinoma

A through substrate structure, an electronic device package using the same, and methods for manufacturing the same are disclosed. First, a via hole pattern is formed by etching an upper surface of a first substrate. A pattern layer of a second substrate is formed on the first substrate by filling the via hole pattern with a material for the second substrate by reflow. A via hole pattern is formed in the pattern layer of the second substrate by patterning the upper surface of the first substrate. Moreover, a via plug filling the via hole pattern is formed by a plating process, for example, thereby forming a through substrate structure, which can be used in an electronic device package.

Through substrate structure, device package having the same, and methods for manufacturing the same

Disclosed are bovine excretion extracts having anticancer and anti-inflammatory activity prepared by a process comprising the step of extracting bovine excretion with a polar solvent selected from the group consisting of lower alcohol, lower ketone, acetonitrile, water and mixtures thereof, a process for preparing the same, and the use thereof as an anticancer agent or adjuvant, or an anti-inflammatory agent.

Bovine excretion extracts having anticancer and anti-inflammatory activity and process for preparing the same

A processed ginseng product with enhanced pharmacological effects is provided due to a heat-treatment at a high temperature of 120.degree. to 180.degree. C. for 0.5 to 20 hours so as to make a ratio of ginsenoside (Rg.sub.3 +Rg.sub.5) to (Rc+Rd+Rb.sub.1 +Rb.sub.2) above 1.0.

Processed ginseng product with enhanced pharmacological effects

Growing community of inventors

Seoul, South Korea

Seung Ki Lee