Konkuk University Glocal Industry-academic Collaboration Foundation

Seung Jun Lee

Yeong Min Park

In Duk Jung

Sung Jae Shin

Jung Hee Park

Byoung Yul Soh

Tae Heung Kang

Provided is an antibacterial composition against carbapenem-resistant gram-negative bacteria which includes, as an active ingredient, adenylate kinase (ADK) protein derived from. The ADK protein derived from, according to the subject matter, has excellent antimicrobial activity against carbapenem-resistant gram-negative bacteria, and thus may be usefully used in a variety of fields as an antibacterial composition.

Antibacterial composition for combating carbapenem-resistant gram-negative bacteria comprising ADK protein as active ingredient

The present invention relates to a composition for preventing or treating sepsis or septic shock including a-derived adenosine kinase (ADK) protein as an active ingredient. The-derived ADK protein according to one exemplary embodiment of the present invention has an effect of inhibit binding between the LPS and cells by binding to LPS, and also has an excellent therapeutic effect against sepsis by enhancing viability in a sepsis animal model and suppressing inflammatory response in the lung and cell death in the spleen.

Compositions for preventing or treating sepsis or septic shock compromising ADK protein as active ingredient

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Yeongju-si, South Korea

Seung Jun Lee