Biocore Co., Ltd.

Seung Jun Kim

Seung Yong Lee

Ji Hoon Kim

Jeong Eun Ahn

Seung Yong Hwang

Joon Soo Park

Jong Pil Youn

Hyo Jung Choi

Moon Ju Oh

The present invention relates to a method for prenatal diagnosis using digital PCR, and more particularly to a method for providing information for diagnosis of chromosomal aneuploidy in a fetus, comprising: (a) extracting DNAs from pregnant woman's blood; (b) classifying the DNAs according to size to obtain DNAs having a size of 1,000 bp or less; (c) performing digital PCR using the obtained DNAs of step (b), for a control gene located on a chromosome not associated with chromosomal aneuploidy and a target gene located on a chromosome associated with chromosomal aneuploidy; (d) calculating a ratio of a quantitative digital PCR value of the target gene to a quantitative digital PCR value of the control gene; and (e) determining that when the ratio calculated in step (d) is 0.70-1.14, a chromosome number of the fetus is normal.

Method for prenatal diagnosis using digital PCR

Growing community of inventors

Gyeonggi-do, South Korea

Seung Jun Kim