Kyowa Hakko Kogyo Co., Ltd.

Kyowa Hakko Kirin Co., Limited

Setsuya Sasho

Kenji Uchida

Hiroyuki Obase

Shunji Ichikawa

Katsuichi Shuto

Yoshimasa Oiji

Susumu Iwamoto

Kyoichiro Iida

Hideyuki Onodera

Hiromasa Kato

Tsutomu Agatsuma

Kazuhiro Hibino

Makoto Suzuki

Kouji Baba

Shingo Kakita

The present invention provides a sterol derivative or a pharmaceutically acceptable salt thereof having an activity to promote proliferation of neural stem cells. Namely, the present invention provides a sterol derivative represented by the general formula (I) (wherein Y represents optionally substituted lower alkyl or the like; Xand Xare the same or different, and represent a bond or the like; R, R, R, R, Rand Rare the same or different, and represent a hydrogen atom or the like; Rand Rare the same or different, and represent a hydrogen atom or the like; Rrepresents a hydrogen atom or the like; Rand Rtogether represent a bond or the like; and Rrepresents a hydrogen atom or the like) or a pharmaceutically acceptable salt thereof. 

Sterol derivative

A furan derivative and a pharmaceutically acceptable salt thereof having gastrointestinal enterokinetic activity which is expected to be used in a broad spectrum of diseases associated with gastrointestinal dyskinesia.

Furan derivatives useful for the treatment of gastro-intestinal disorders

Growing community of inventors

Shizuoka, Japan

Setsuya Sasho