Astra Lakemedel Aktiebolag

Seth O Thorberg

Sven O Ogren

Svante Bertil Ross

Ulf H Lindberg

Karl S Bengtsson

Compounds having antipsychotic activity, characterized by the formula ##STR1## in which formula R.sub.o and R.sub.1 are the same or different and are each selected from hydrogen, halogen, alkyl having 1, 2 or 3 carbon atoms, alkoxy having 1, 2 or 3 carbon atoms, and trifluoromethyl, and R.sub.2 is selected from hydrogen, halogen, alkyl having 1, 2 or 3 carbon atoms, alkoxy having 1, 2 or 3 carbon atoms, and trifluoromethyl, pharmaceutical compositions containing them, and a method for the treatment of psychoses.

Anti-psychotic phthalimidine derivatives

A compound of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, in which formula the group R.sup.0 is selected from the group consisting of hydrogen, chlorine, bromine, methyl, trifluoromethyl and methoxy. Pharmaceutical compositions containing these compounds are useful for treatment of depressive disorders.

Compounds having antidepressive activity

A compound of the formula ##STR1## and pharmaceutically acceptable acid addition salts thereof, in which formula the group R.sup.o is trifluoromethyl. Pharmaceutical compositions containing these compounds are useful for treatment of depressive disorders.

Trifluoromethyl substituted compounds having antidepressive activity

A compound of the formula ##STR1## and pharmaceutically acceptable acid addition salts thereof, in which formula the group R.sup.o is selected from hydrogen, chlorine, bromine, methyl, trifluoromethyl and methoxy. Pharmaceutical compositions containing these compounds are useful for treatment of depressive disorders.

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Jarna, Sweden

Seth O Thorberg