University of Dundee

University Court of the University of Dundee

Seth Lawrence Schor

Ana Maria Schor

Rodolfo Marquez

David George Norman

The described invention relates to compounds (I) which modulate cell migration, and find use in, for example, wound healing, cancer progression and angiogenesis. All definitions as in claim. 

Cell migration modulating compounds

The described invention relates to compounds which modulate cell migration, and find use in, for example, wound healing, cancer progression and angiogenesis.

A recombinant polynucleotide encoding migrating stimulating factor (MSF) or variants or fragments or derivatives or fusions thereof or fusions of said variants or fragments or derivatives. Reagents are disclosed which can distinguish MSF and fibronectin, and which can distinguish polynucleotides which encode MSF or fibronectin. These reagents are believed to be useful in, for example, diagnosing cancer. MSF or variants or fragments or derivatives or fusions thereof, or fusions of said variants or fusions or derivatives, are useful in modulating cell migration and in wound healing.

Polypeptides, polynucleotides and uses thereof

A compound with a relative molecular mass of less than 15000 comprising the peptide Ile-Gly-Asp (IGD) or a peptide or non-peptide mimic thereof. The compounds may be used to modulate cell migration and are useful in angiogenesis.

Growing community of inventors

Dundee, United Kingdom

Seth Lawrence Schor