Varian Medical Systems, Inc.

Leland Stanford Junior University

Varian Medical Systems Technologies, Inc.

Sergey Povzner

Hassan Mostafavi

Andrew G Jeung

Herbert F Cattell

Paul J Keall

Alexander Sloutsky

Amit Ramakant Sawant

Yelin Suh

A method of monitoring a patient includes obtaining a first image of an object, obtaining a second image of the object, determining a level of similarity between the first and second images, obtaining a third image of the object, determining a level of similarity between the first and third images, analyzing a time series of values that includes the determined level of similarity between the first and second images and the determined level of similarity between the first and third images, and determining a state of the patient based at least on a result of the act of analyzing.

Systems and methods for determining a state of a patient

A marker system includes a marker, and a positioner coupled to the marker, the positioner configured to position the marker from a first predetermined position to a second predetermined position. A method of providing a marker system includes obtaining a first data representative of a first predetermined position, obtaining a second data representative of a second predetermined position, and moving a set of one or more markers from the first predetermined position to the second predetermined position, wherein the set of one or more markers is moved using a positioner. A method of using a marker system includes detecting a marker when the marker is located at a first position, moving the marker from the first position to a second position using a positioner, and detecting the marker when the marker is located at the second position.

Marker system and method of using the same

A method of continuous real-time monitoring and positioning of multi-leaf collimators during on and off radiation exposure conditions of radiation therapy to account for target motion relative to a radiation beam is provided. A prediction algorithm estimates future positions of a target relative to the radiation source. Target geometry and orientation are determined relative to the radiation source. Target, treatment plan, and leaf width data, and temporal interpolations of radiation doses are sent to the controller. Coordinates having an origin at an isocenter of the isocentric plane establish initial aperture end positions of the leaves that is provided to the controller, where motors to position the MLC midpoint aperture ends according to the position and target information. Each aperture end intersects a single point of a convolution of the target and the isocenter of the isocentric plane. Radiation source hold-conditions are provided according to predetermined undesirable operational and/or treatment states.

Method to track three-dimensional target motion with a dynamical multi-leaf collimator

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Burlingame, CA, United States of America

Sergey Povzner