Cancer Research Technology Limited

Affitech Research As

Sergej Michailovic Kiprijanov

Remko Griep

Urs Beat Hagemann

Herald Reiersen

Anita Kavlie

The present invention provides antibodies which bind to an epitope in the extracellular domain of human CC chemokine receptor 4 (CCR4) and which are capable of inhibiting the binding of macrophage-derived chemokine (MDC) and/or thymus and activation regulated chemokine (TARC) to CCR4. Also provided are inter alia immunoconjugates and compositions comprising such antibodies and methods and uses involving such antibodies, particularly in the medical and diagnostic fields.

Antibodies which bind to the human CC chemokine receptor 4 and uses thereof

Nucleic acid molecules encoding antibodies which bind CCR4 and uses thereof

The present invention provides antibodies which bind to CXC chemokine receptor 4 (CXCR4) and which do not induce significant apoptosis of CXCR4 expressing cells. Also provided are inter alia immunoconjugates and compositions comprising such antibodies and methods and uses involving such antibodies, particularly in the medical and diagnostic fields.

Antibodies

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Oslo, Norway

Sergej Michailovic Kiprijanov