Institut National De La Sante Et De La Recherche Medicale

Centre Hospitalier Regional Et Universitaire De Lille (chru)

Université De Lille

Université De Lille 2 Droit Et Santé

Inserm (institut National De La Sante Et De La Recherche Medicale)

Centre Hospitalier Régional Et Universitaire De Lille

Inserm

Serge Mordon

Nacim Betrouni

Pascal Delepôrte

Maximilien Vermandel

Pierre Nevoux

Pierre Colin

Clement Dupont

Laurent Mortier

Nicolas Reyns

Bertrand Leroux

Clément Dupont

System () for treatment by photodynamic therapy comprising an illuminating member () which comprises: &#x2014;a core () carrying a light emitting surface (), and &#x2014;a hollow sheath () adapted to receive the core () with the light emitting surface () arranged within a balloon (), the balloon () comprising a wall () which has an inner surface delimiting an internal space, and an outer surface, the wall () being flexible, wherein the internal space of the balloon () has a variable capacity, the wall () of the balloon () being elastically extendible and the balloon () presenting a plurality of inflated states in each of which the internal space is filled with a volume of light diffusing solution, and wherein the system further comprises a support provided with a transfer function relating the volume of light diffusing solution of each inflated state with at least one of a corresponding distribution of light power at the outer surface of the wall () of the balloon () and a corresponding time of illumination for providing a determined dose of light energy.

System for treatment by photodynamic therapy of a cavity of a patient's body and method for preparation of such system

The system comprises: &#x2014;a bundle of light fibers () connected to a light-emitting source (), and both transmitting light inside the light fiber and emitting light toward a treatment volume (V), &#x2014;a temperature-modifying system attached to the bundle of light fibers () to modify temperature in the treatment volume (V).

Light emitting system

An optical fiber mode scrambler adapted to give a determined bending to an optical fiber inserted in the mode scrambler, the mode scrambler having a general extension direction X, the mode scrambler having a morphology adapted to give the optical fiber a direction along X at the entry of the scrambler, and then to bend the fiber to bring the fiber substantially in the X, Y plan in the &#x2212;X and Y directions, before bringing the fiber in a rotation around the X axis substantially in the Y, Z plan in the anti clockwise direction for one full rotation, and then bending the fiber to bring the fiber substantially in the X, Y plan in the &#x2212;X and &#x2212;Y directions, and then bending the fiber to give the optical fiber a direction along X at the exit of the scrambler.

Optical fiber mode scrambler

Prostate phantom comprising an artificial prostate () and an artificial lesion arranged within the artificial prostate (), wherein the artificial prostate () comprises: a first part () mimicking a peripheral zone of a zonal anatomy of the prostate, the first part () being made of a first artificial tissue and comprising a closed outer surface, at least a second part () separate from the first part () and mimicking at least a second zone of the zonal anatomy of the prostate, the second part () being made of a second artificial tissue and comprising a closed outer surface, the first () and second () parts contacting each other along an interface mimicking a boundary between the peripheral zone and the second zone.

Prostate phantom, system for planning a focal therapy of a prostate cancer comprising such prostate phantom and method for planning a focal therapy of a prostate cancer implementing such system

Growing community of inventors

Lille, France

Serge Mordon