Transgene S.a.

Other

Association Francaise Contre Les Myopathies

Serge Braun

Frederic Perraud

The invention concerns the use of a nucleic acid capable of expressing beta-interferon for the preparation of a pharmaceutical composition for the treatment of an immune disease.

Treatment of immune diseases

Described is the use of magnesium (Mg) for the preparation of a therapeutic composition for the introduction of a polynucleotide into a cell in vivo.

Use of magnesium (Mg2+) for the preparation of a therapeutic composition for transfection of a polynucleotide into a cell and compositions useful in gene therapy

Described is the use of lithium (Li ) for the preparation of a therapeutic composition for the introduction of a polynucleotide into a cell.

Use of lithium (Li&plus;) for the preparation of a composition for transfection of a polynucleotide into a cell and compositions useful in gene therapy

Process for production of mammalian cell lines

Described is the use of a nuclease inhibitor or of interleukin-10 (IL-10) for the preparation of a therapeutic composition for improving transfection of a polynucleotide into a cell, and to compositions comprising a mixture of polynucleotide and nuclease inhibitor and/or interleukin-10.

Use of G-actin for improving transfection of a polynucleotide into a cell

Human myoblast cell lines and their uses

The invention relates to a composition, kit and methods of using the compositions and kits. The composition comprises a compound which disorganizes or degrades the extracellular matrix of a cell and a nucleic acid of interest. The composition or kit is contemplated for use in gene transfer and gene therapy.

Growing community of inventors

Dorlisheim, France

Serge Braun