Amolifescience Co., Ltd.

Konkuk University Industrial Cooperation Corp

Kollodis Biosciences, Inc.

Seonho Jang

Chan Kim

In Yong Seo

Song Hee Koo

Hui-Gwan Goo

Dong-Sik Seo

Kyuwon Baek

Seung Hoon Lee

Ji Hyun Lee

Sang-eun Park

Sangjae Lee

Ssang-Goo Cho

Gwang-Mo Yang

Bongjin Hong

Jihye Won

Chulbae Yoo

Described is a three-dimensional (3D) microenvironment presenting defined biochemical and physical cues that regulate cellular behavior and use of the microenvironment. A composition to form the 3D microenvironment is provided by combining one or more natural or synthetic polymeric materials and substrate proteins recombinantly or chemically functionalized with a variety of bioactive peptides such as extracellular matrix-derived or growth factor-derived peptides. Also described are devices and methods for screening for optimal combinations of the bioactive motifs in order to create an extracellular microenvironment that can regulate specific cellular behavior such as cell growth, proliferation, migration or differentiation.

Defined three dimensional microenvironment for cell culture

This disclosure provides for a three-dimensional (3D) microenvironment presenting defined physical or mechanical cues that regulate cellular behavior and use of the matrix. The disclosure also provides for devices and methods for screening for optimal combinations of physical and mechanical cues in order to create a microenvironment that can regulate specific cellular behavior such as cell growth, proliferation, migration or differentiation.

Defined three-dimensional microenvironment for stem cell

Growing community of inventors

Seoul, South Korea

Seonho Jang