Samsung Electronics Co., Ltd.

Ls Automotive Technologies Co., Ltd.

Rznomics Inc.

Seoul National University

National Cancer Center

Industry-academic Cooperation Foundation, Dankook University

Postech Academy-industry Foundation

Posco

Dong-a University Research Foundation for Industry-academy Cooperation

Daewon Pharm., Co., Ltd.

Bexcore Co., Ltd.

Seong-Wook Lee

Yeon-Muk Choi

Byung-Cheol Na

Da-Hee Sim

Won-Yong Lee

Ji Hyun Kim

Jin-Sook Jeong

Chang-Yeul Kwon

Seong-Cheol Kim

In-Hoo Kim

Seung Ryul Han

Chang-Ho Lee

Chang-Hyun Lee

Lochan Verma

Dae-Hyun Kim

Chang Ho Lee

Woo-jin Park

Jin-Wook Lee

Sang-Wook Lee

Jae-Eun Kang

Kyung-ik Cho

Jae-Moon Jo

Chil-Youl Yang

Young-ju Lee

Se-young Shin

Seung-seop Shim

Young-Ho Ryu

Chong-Min Lee

Yun-Hee Kim

Young-Joo Lee

Sang Jin Lee

Jae-moon Jo

Dong-Hwi Roh

Guoping Fan

Suk-Jin Yun

Yeon-Su Lee

Ho-seok Lee

Julan Hsu

Joong-suk Park

Moon-young Choi

Byeong-Ho Lee

Young-jun Yoon

Jong-Hoon Lim

Seung-Seop Shim

Hyo-Sun Shim

Sang Young Han

Jin Sook Jeong

Mi Ha Ju

Hakirat Singh

Seung-Hee Hong

Yoon-Jong Lee

Haeng-Im Jung

Kyung-Sook Shin

Seung Ryul I Han

Heon-Kyo Sim

Kyung Hyun Lee

Seongcheol Kim

Eun Yi Cho

Ho-Seok Lee

Se-Young Shin

Joong-Suk Park

A self-circularization RNA construct that can be expressed in a DNA vector and simultaneously circularized through a self-targeting and splicing reaction to form a circRNA is disclosed. The circRNA can consist only of a gene of interest which can be a coding, non-coding, or a combination thereof. The gene of interest has the advantage of being able to rapidly express a peptide or protein. The formed circRNA has a circular structure and has a stable and high half-life because 5′ and 3′ ends are not exposed. Accordingly, functional RNA such as miRNA, anti-miRNA, siRNA, shRNA, aptamer, functional RNA for gene/RNA editing, ADAR (adenosine deaminase acting on the RNA)-recruiting RNA, mRNA vaccine, mRNA therapeutic agent, vaccine adjuvant, and CAR-T mRNA can be produced as a stable circRNA in cells.

Construct of self-circularization RNA

A method and an apparatus for estimating direction of arrival of radar reception signal using antenna array extrapolation. Obtained is a transformation matrix representing a relationship between phases of reception signals received through ito (N−2+i)antennas and a phase of a reception signal received through (N−1+i)antenna in a ULA antenna unit including N actual antennas. A phase of a virtual reception signal received through a new (N+i)virtual antenna is generated by multiplying values corresponding to phases of the reception signals received through (i+1)to (N−1+i)antennas by the transformation matrix. A magnitude of the virtual reception signal received through the (N+i)virtual antenna is obtained by averaging magnitudes of the reception signals received through ito (N−1+i)antennas.

Method and apparatus for estimating direction of arrival of radar reception signal using antenna array extrapolation

A trans-splicing ribozyme capable of splicing a rhodopsin transcript at a target splicing site and containing a sequence that is capable of complementarily binding to a target binding site of the rhodopsin transcript is disclosed. The trans-splicing ribozyme may further containing a desired rhodopsin transcript at 3'-end. The trans-splicing ribozyme may further contains an antisense sequence that is complementary to a region downstream the target binding site of the rhodopsin transcript. A nucleotide molecule encoding the trans-splicing ribozyme is also disclosed. Delivery systems to delivery the nucleotide molecule and/or the trans-splicing ribozyme to target tissue or cells as well as uses of the trans-splicing ribozyme, the nucleotide molecule, delivery systems, or pharmaceutical compositions containing any of them are also disclosed.

Trans-splicing ribozyme targeting rhodopsin transcript and uses thereof

A cancer-specific trans-splicing ribozyme and a use thereof are disclosed. The trans-splicing ribozyme does not act on normal tissue, but is specifically expressed in cancer tissue. Therefore, it is very safe and has excellent expression efficiency at the post-transcription level, and thus can be effectively used in treatment of cancer.

Cancer-specific trans-splicing ribozymes and use thereof

Disclosed is a resolver, which includes a stator having at least one excitation coil and at least one output coil, and a rotor disposed at a center space in the stator with a predetermined gap from the stator, the rotor rotating based on a rotary shaft to change a gap permeance with respect to the stator, wherein an area ratio (Ar/As) between the stator and the rotor satisfies Equation 1 below to prevent magnetic saturation of the resolver, improve measurement precision and reduce manufacture costs without increasing a size or weight of the resolver:0.22&#x2264;&#x2264;0.37&#x2003;&#x2003;Equation 1

Resolver

A wireless power transmitter configured to wirelessly transmit power to an electronic device is provided. The wireless power transmitter includes a power transmission antenna including a plurality of patch antennas for wirelessly transmitting power, a sensor, and a processor, wherein the processor may be configured to create a first clutter map representing a reflection characteristic of an object positioned around the wireless power transmitter based on, at least, first data obtained by the sensor during a first period, store the first clutter map, compare a difference between the first clutter map and second data obtained by the sensor during a second period with data contained in the first clutter map, create a second clutter map corresponding to the second period based on a result of the comparison, determine a position of an organism using the second data and the second clutter map, and control the power transmission antenna such that a magnitude of the RF wave is less than a predetermined value based on the position of the organism.

Wireless power transmitter and method for controlling the same

Disclosed is a resolver, which includes a stator made of a magnetic material and having a plurality of teeth and a plurality of slots alternately formed at an inner side thereof; insulation covers respectively having a tooth insulating unit formed at an inner side thereof corresponding to the teeth and mounted to the stator at both upper and lower surfaces of the stator; and coils wound on the teeth with the tooth insulating unit being interposed therebetween, wherein a coil occupying ratio per slot, which is defined by the following equation and represents a ratio of area occupied by the coils in a slot to which the insulation covers are fixed, is 35% or below:Coil occupying ratio per slot=(area occupied by coils in a single slot)/(area of a single slot)&#x2003;&#x2003;Equation.

Disclosed is a resolver robust against external noise and having a reduced error in the detection of a rotation angle, which includes a stator made of a magnetic material and having a plurality of teeth and a plurality of slots alternately formed at an inner side thereof, insulation covers respectively having a tooth insulating unit formed at an inner side thereof corresponding to the teeth and mounted to the stator at both upper and lower surfaces of the stator, and coils wound on the teeth with the tooth insulating unit being interposed therebetween, wherein regarding winding widths of coils located at an outermost circumference among the wound coils, a ratio of a shortest winding width to a longest winding width is 0.69 or above and 1 or below.

Disclosed is a resolver, which includes a stator having at least one excitation coil and at least one output coil, and a rotor disposed at a center space in the stator with a predetermined gap from the stator, the rotor rotating based on a rotary shaft to change a gap permeance with respect to the stator, wherein the stator includes a back yoke having a ring-shaped body, and a plurality of teeth formed at an inner circumference of the back yoke so that the excitation coil and the output coil are wound thereon, wherein the rotor includes a ring-shaped body having a center hole into which the rotary shaft is inserted, and a plurality of salient poles formed at an outer circumference of the ring-shaped body.

Disclosed is a resolver, which includes a stator having at least one excitation coil and at least one output coil, and a rotor disposed at a center space in the stator with a predetermined gap from the stator, the rotor rotating based on a rotary shaft to change a gap permeance with respect to the stator, wherein a thickness (tr) of the rotor and a thickness (ts) of the stator satisfies the equation: tr&#x2212;ts&#x2265;0.7 [mm], thereby efficiently offsetting an influence caused by an assembly error, which is commonly generated when assembling a resolver, improving the measurement precision, facilitating a resolver designing work and reducing manufacture costs.

The present invention relates to a recombinant adenovirus with increased in-vivo safety, tissue specificity, and anticancer activities, and a use thereof. Specifically, the recombinant adenovirus comprising: a promoter of the liver tissue-specific phosphoenolpyruvate carboxykinase (PEPCK) gene; a trans-splicing ribozyme which is operably linked to the promoter and acts on a cancer-specific gene; a therapeutic gene or a reporter gene which is linked to the 3' exon of the ribozyme; and a serotype 35 fiber knob and a serotype 5 shaft, in which the orf4 gene is deleted from adenovirus E1, E3 and E4 orf1, shows remarkable in-vivo safety, high specificity for a target tissue, and remarkable anticancer effects, and thus can be useful for an anticancer drug or a cancer diagnostic agent as a gene delivery vector.

Recombinant adenovirus with increased safety and anticancer activities, and use thereof

The present invention relates to an aptazyme comprising an aptamer for hepatitis C virus (HCV) RNA-encoding component; a hammerhead ribozyme comprising an antisense sequence to microRNA at the site released by self-cleavage; and a communication module sequence that connects the aptamer and hammerhead ribozyme and triggers a self-cleavage activity of the hammerhead ribozyme upon binding of the aptamer with the HCV RNA-encoding component. The present aptazyme inhibits microRNA activity specifically in HCV proliferating cells and thus a composition of the present invention comprising the aptazyme can be effectively used for treatment of HCV-related diseases.

Aptazyme capable of selective silencing of target miRNA by releasing an antisense sequence in hepatitis C virus-infected cells and use thereof

Provided are RNA aptamer specifically binding to cancer metastasis-inducing domain of CEA (Carcinoembryonic antigen), a composition for prevention and/or inhibition and/or diagnosis of cancer metastasis containing the same as an active ingredient, and a method of prevention and/or inhibition and/or diagnosis of cancer metastasis using the same.

RNA aptamer specifically binding to carcinoembryonic antigen and use thereof

To check security of an Access Point (AP) in a wireless communication system, an operating method of a terminal includes, before completing connection to the AP, receiving a frame that informs the terminal of existence of the AP; extracting security test information from the frame; and testing the security of the AP using the security test information.

Apparatus and method for identifying wireless network provider in wireless communication system

Provided are a method and an apparatus for transmitting a packet in a wireless local area network (LAN), the method including determining whether a packet, which does not expire during the current transmission opportunity (TXOP) but will expire before a next TXOP is secured, exists or not based on a time-to-live (TTL) of the packet; if it is determined that the packet does not expire during an expansion of the current TXOP, expanding the current TXOP; and transmitting the packet to a receiving station.

Method and device for sending packets on a wireless local area network

Growing community of inventors

Seoul, South Korea

Seong-Wook Lee