Cj Corporation

Seong Hwan Cho

Yong Sik Youn

Dong Kwon Lim

Kwang Hyeg Lee

Choong Sil Park

Young Hoon Kim

Kyung Mi Park

Sung Hak Jung

Kyu Jeong Yeon

Sung Hak Lee

Hae Tak Jin

Hyun Suk Kang

Yun Taek Jung

Hyuk Koo Lee

Yun Cheul Kim

Jun Hee Cheon

Eun Ju Jeong

Myeong Yun Chae

Hea Ran Suh

Provided is a method of preparing an optically pure compound having formula 1 or its salts. The method includes: reacting (R)-2-(4-methoxy-3-aminosulfonyl-phenyl)-1 -methylethylamine or its salts with a compound selected from the group consisting of chloroacetic acid, bromoacetic acid, fluoroacetic acid, iodoacetic acid, &#x3b1;-halogenoacetic acid anhydride, and &#x3b1;-halogenoacetyl halide in the presence of a base or an acylating agent.

Method of preparing optically pure phenethylamine derivatives

A novel crystalline organic acid salt of amlodipine having improved physiochemical properties, a preparation method thereof and a pharmaceutical composition comprising the same are provided.

Crystalline organic acid salt of amlodipine

Disclosed are a novel organic acid salt of amlodipine, its preparation method, and a pharmaceutical composition containing as a therapeutically active ingredient the same.

Organic acid salt of amlodipine

Disclosed are a novel organic acid salt of amlodipine, its preparation method, and a pharmaceutical composition containing the same as a therapeutically active ingredient.

Disclosed are a novel organic acid salt of amlodipine with superb physicochemical properties, its preparation method, and a pharmaceutical composition containing the same as a therapeutically active ingredient.

Growing community of inventors

Suwon-si, South Korea

Seong Hwan Cho