Samsung Electronics Co., Ltd.

Yonsei University

Seon Hui Shim

Soo Yeon Jung

Kyung Ah Kim

Jeong Min Kim

Ji Min Lee

Won Suk Lee

Yun Jeong Song

Hyeon-seok Yoo

Sun Young Rha

Woo Sun Kwon

A method for predicting and/or monitoring the efficacy of a c-Met inhibitor using a biomarker; a method for selecting a subject suitable for the application of a c-Met inhibitor using a biomarker; and a method for preventing and/or treating cancer comprising administering a c-Met inhibitor to the selected subject.

Prediction of effect of a c-Met inhibitor using mutation of KRAS or BRAF

A biomarker for predicting and/or monitoring the efficacy of a c-Met inhibitor; a composition for predicting and/or monitoring the efficacy of a c-Met inhibitor, comprising a material detecting the biomarker; a composition for selecting a subject suitable for the application of a c-Met inhibitor, comprising a material detecting the biomarker; a method for predicting and/or monitoring the efficacy of a c-Met inhibitor using the biomarker; a method for selecting a subject suitable for the application of a c-Met inhibitor using the biomarker; and a method for preventing and/or treating cancer comprising administering a c-Met inhibitor to the selected subject.

Method for predicting efficacy of c-Met inhibitor

A method of preventing and/or treating a cancer, the method including co-administering a dual inhibitor of c-Met (hereinafter, 'c-Met inhibitor') and an IGF-1R inhibitor to a subject in need thereof and a use of IGF-1R as a marker for resistance to a c-Met inhibitor.

Combination therapy using c-Met inhibitor and IGF-1R inhibitor for c-Met inhibitor resistant cancers

Growing community of inventors

Daejeon, South Korea

Seon Hui Shim