Toolgen Inc.

Seoul National University

Vtouch Co., Ltd.

Institute for Basic Science

Seokjoong Kim

So Yeon Kim

Jin-Soo Kim

Jong Min Kim

Dong Woo Song

Jae Young Lee

Jung Min Lee

Chunghoon Kim

Gyu-bon Cho

Jeong Hun Kim

Young-Hoon Kim

Sung Wook Park

Byung Ok Choi

Sojung Kim

Young Bin Hong

Hee Sook Bae

Min Hee Jung

Seung Woo Cho

Joonsun Lee

Eunji Shin

Kyu Jun Lee

Jeongjoon Lee

Un-Gi Kim

Jung-Min Lee

Beomho Lee

Kang In Lee

The present invention relates to an expression control composition for controlling the expression of a duplicate gene or a method using the same. In addition, the present invention relates to a method of treating or improving a disease caused by gene duplication using the expression control composition for controlling the expression of a duplicate gene.

Artificial genome manipulation for gene expression regulation

The present invention relates to an artificially manipulated neovascularization-associated factor for regulating neovascularization and a use thereof. More particularly, the present invention relates to a system for artificially regulating neovascularization, which includes an artificially manipulated neovascularization-associated factor for regulating neovascularization and/or a composition for artificially manipulating the neovascularization-associated factor. In a specific aspect, a neovascularization regulatory system including a neovascularization-associated factor such as artificially manipulated VEGFA, HIF1A, ANGPT2, EPAS1, or ANGPTL4 and/or an expression product thereof is provided.

Artificially-manipulated neovascularization regulatory system

Provided is a platform for expressing a protein of interest by artificially manipulating the liver, and more particularly, to a platform for alleviating or treating a genetic disorder or improving a body function by inducing expression by inserting a transgene (e.g., a therapeutic gene) which can function or be expressed normally, into a high-expression secretory gene, instead of a disease gene which functions or is expressed abnormally. The high-expression secretory gene includes the HP or APOC3 gene. The transgene includes one that is highly expressed using a promoter in a hepatocyte genome and is secretory out of the cell.

Platform for expressing protein of interest in liver

The present invention relates to an artificially engineered CRISPR/Cas9 system. More particularly, the present invention relates to an artificially engineered CRISPR enzyme having enhanced target specificity and a use of an artificially engineered CRISPR/Cas9 system including the same enzyme in genome and/or epigenome manipulation or modification, genome targeting, genome editing, and in vitro diagnosis, etc.

Target-specific CRISPR mutant

Disclosed are a method and an apparatus for accurately detecting a gesture from a user's motion using a user-based spatial coordinate system. A method for detecting a gesture in a user-based spatial coordinate system comprises the steps of: setting a user-based spatial coordinate system using a first body coordinate corresponding to a first body part of the user as a starting point; analyzing the motion vector state of a second body coordinate corresponding to a second body part of the user in the user-based spatial coordinate system over time; and detecting the user's gesture on the basis of a change in the motion vector state.

Method and apparatus for detecting gesture in user-based spatial coordinate system

A control method for allowing a user to specify an electronic device and switch it to a speech recognition mode is provided. With the optimum control method and the electronic device utilizing the method, a voice command may be transmitted to the electronic device more quickly and effectively regardless of the circumstances, and the electronic device may be specified through gesture recognition to enable transmission of the voice command, so that the voice command may be effectively executed without needing a user to learn or memorize a name or the like of the electronic device in advance for speech recognition. Further, it is possible to more accurately recognize a gesture that is a preliminary step for transmitting a voice command to the electronic device, thereby improving the recognition rate and preventing malfunction.

Optimum control method based on multi-mode command of operation-voice, and electronic device to which same is applied

Growing community of inventors

Seoul, South Korea

Seokjoong Kim