Yonsei University

Seo Ryung Bae

Byunghoon Kang

Seungjoo Haam

Yong-min Huh

Hyun-Ouk Kim

Jaemoon Yang

Jihye Choi

Jin-Suck Suh

Ilkoo Noh

Eunji Jang

Myeong-Hoon Kim

Yoochan Hong

Eun Bi Choi

Provided are polyaniline coordinated with a transition metal, a core-shell nanoparticle including the same as a core, and preparation methods thereof. According to the polyaniline coordinated with a transition metal and the nanoparticle of the present application, it is possible to prepare polyaniline coordinated with a transition metal using an oxidizing agent having a core-shell structure and including the transition metal and a nanoparticle including the same as a core. The polyaniline prepared as such is in a doped state, and, thus, a preparation process is simple. Further, dispersibility with respect to a solvent is improved, and a band gap level of the polyaniline can be easily regulated.

Polyaniline coordinated with transition metal and preparation method thereof

The present invention relates to an amphiphilic nanoparticle specific to a biomarker, and more particularly, provides an amphiphilic nanoparticle which may be used as a diagnosis or treatment-type drug or gene carrier by selectively recognizing a proteolytic enzyme specifically expressed in a cellular membrane of a specific cell, and then being bound to the proteolytic enzyme to efficiently achieve the intracellular uptake and selective cleavage. The amphiphilic nanoparticle of the present invention may be used in the diagnosis or therapy of a disease.

Biomarker specific amphiphilic nanoparticles

Growing community of inventors

Seoul, South Korea

Seo Ryung Bae