Kasina Laila Innova Pharmaceuticals Private Limited

Sengupta Krishanu

Ganga Raju Gokaraju

Rama Raju Gokaraju

Sudhakar Kasina

Trimurtulu Golakoti

Kiran Bhupathiraju

Venkateswarlu Somepalli

Venkata Kanaka Ranga Raju Gokaraju

Venkata Krishna Raju Alluri

The present invention discloses triazene analogs of the general formula (I) and formula (II), their tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts thereof for the metastatic malignant melanoma and other cancers including but not limited to lymphomas, sarcomas, carcinomas, and gliomas. The invention further discloses a process for the preparation of the above said triazene analogs of formula (I) and formula (II), and their pharmaceutically acceptable compositions.

Anti-cancer drugs and uses relating thereto for metastatic malignant melanoma and other cancers

Selenopheno triazene analogs, their compositions, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts and mixtures thereof are useful for the treatment of metastatic malignant melanoma and other cancers. The selenopheno triazene analogs have the general formulae (I) or (II): wherein the substituents R, R, R, R, and Rare as described in the specification. Other cancers include which may be treated with these compounds include, but are not limited to, malignant melanoma, leukemia, lymphomas (Hodgkins and non-Hodgkins), sarcomas (Ewing's sarcoma), brain tumors, central nervous system (CNS) metastases, gliomas, carcinomas such as breast cancer, prostate cancer, lung cancer (small cell and non-small cell), colon cancer, pancreatic cancer, Head and Neck cancers and oropharyngeal squamous cell carcinoma.

Anti-cancer drugs, and uses relating for malignant melanoma and other cancers

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Andhra Pradesh, India

Sengupta Krishanu