Yungjin Pharm Co., Ltd.

Aeon Medix Inc.

Seng Jin Choi

Yong Song Gho

Yoon Keun Kim

Ji Hyun Kim

Sung Wook Hong

Eun Young Lee

The present disclosure relates to a method of assessing a subject's susceptibility to a vascular disease. The method may comprise providing a concentrated population of extracellular vesicles contained in a biological material obtained from a subject, processing the concentrated population to determine if the concentrated population contains a 16S rRNA sequence of, and upon determining that the concentrated population contains a 16S rRNA sequence of, further determining that the subject is potentially susceptible to a vascular disease.

Extracellular vesicles derived from Gram-positive bacteria, and use thereof

The present application relates to extracellular vesicles (EVs) derived from gram-positive bacteria. In detail, the present application provides animal models of disease using extracellular vesicles derived from gram-positive bacteria, provides a method for screening an active candidate substance which is capable of preventing or treating diseases through the animal models of disease, provides vaccines for preventing or treating diseases caused by extracellular vesicles derived from gram-positive bacteria, and provides a method for diagnosing the causative factors of diseases caused by gram-positive bacteria using extracellular vesicles.

Extracellular vesicles derived from gram-positive bacteria, and use thereof

Growing community of inventors

Pohang-si, South Korea

Seng Jin Choi