Toyo Jozo Company, Ltd.

Seiji Katsumata

Naoki Muto

Tadashiro Fujii

Tetsu Saito

Masaru Otani

Shuzo Satoi

Mitsuo Hayashi

Masaru Ono

A novel microorganism species belonging to the genus Micromonospora, i.e. Micromonospora sp. A 11725 is found to be capable of producing novel macrolide antibiotics A 11725 I, A 11725 II and A 11725 III. Novel antibiotics A 11725 Ia and A 11725 IIa are also found to be derived by chemical modification of the antibiotics A 11725 I and A 11725 II, respectively. All of these antibiotics or salts thereof exhibit excellent antibacterial and anti-mycoplasmal activities against various microorganisms such as Staphylococcus or Mycoplasma, and therefore useful for various purposes including medicaments.

Novel macrolide antibiotics and preparation thereof

Growing community of inventors

Susono, Japan

Seiji Katsumata