Mitsui Chemicals, Inc.

Mitsui Toatsu Chemicals, Incorporated

Seiichi Watanabe

Tadashi Araki

Tomonori Hidesaki

Kiyoteru Nagahara

Mitsuo Koito

Keita Nishida

Tamotsu Asano

Takeya Abe

Kenju Sasaki

Yoshinori Tanaka

Daisuke Mochizuki

Hitoshi Takahashi

Mitsufumi Wada

Takashi Morishige

Katsutoshi Ishikawa

Kiyoshi Ito

Toshiaki Kuwatsuka

Kiyoshi Itou

Nozomi Takebayashi

Toshiyuki Kouno

Fuminobu Yoshimi

Toshihisa Tachibana

This invention relates to DNA encoding a novel enzyme having activity of synthesizing D-serine from formaldehyde and glycine, recombinant DNA constructed by integrating such DNA into a vector, a transformant transformed with the recombinant DNA, and a method for producing D-serine from formaldehyde and glycine with the use of the enzyme.

DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same

The invention provides: an isopropyl alcohol-producing bacterium which has an acetoacetate decarboxylase activity, an isopropyl alcohol dehydrogenase activity, a CoA transferase activity and a thiolase activity having been imparted thereto and is capable of producing isopropyl alcohol from a plant-derived material; a method of producing isopropyl alcohol whereby isopropyl alcohol is produced from a plant-derived material by using this isopropyl alcohol-producing bacterium; and an apparatus therefor.

Isopropyl alcohol-producing bacterium and method of producing isopropyl alcohol using the same

This invention relates to DNA encoding an enzyme having activity of synthesizing D-serine from formaldehyde and glycine, recombinant DNA constructed by integrating such DNA into a vector, a transformant transformed with the recombinant DNA, and a method for producing D-serine from formaldehyde and glycine with the use of the enzyme.

The invention is to provide a process for effectively removing impurities contained in an amide compound-containing solution by making an amide compound-containing solution, particularly an amide compound-containing solution produced by a hydration reaction of a nitrile compound by using a microorganism fungus body containing nitrile hydratase or a processed product of the microorganism fungus body, in contact with activated carbon under acidic conditions.

Method of purifying amide compound

The invention is a process for continuously producing an amide compound by reacting a microorganism fungus body containing nitrile hydratase or a processed product of the microorganism fungus body with a nitrile compound in an aqueous medium, characterized in that after contacting said fungus body or said processed product of said fungus body with said nitrile compound in said aqueous medium, a reaction solution thus obtained is further subjected to reaction under conditions having a plug flow region, and according to the invention, an amide compound aqueous solution of a high concentration a high purity can be easily obtained in an extremely high conversion rate of a nitrile compound without a condensation process.

Process for producing amide compounds

Process for the preparation of thiazolecarboxylic acid chlorides

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Mobara, Japan

Seiichi Watanabe