Nippon Soda Co., Ltd.

Seiichi Uchida

Nobuo Mochizuki

Nobuhiro Umeda

Yasuyuki Shiinoki

Hirokazu Yamada

Hiromi Horikoshi

Seiichi Ikeyama

Shiro Tsubokura

Izumi Kumita

Tadayuki Nishibe

Fumie Shirato

Hiroko Momoe

Kunihito Ito

Hiromi Ichihara

Mitsumasa Takada

Hiroyuki Miyamoto

The present invention relates to a compound represented by formula (1): (wherein, R1, R2, R3 and R4 respectively and independently represent a hydrogen atom or a Calkyl group, and n represents an integer of 1 or 2) and a production process thereof, as well as an antioxidant that contains the compound as its active ingredient, and a kidney disease treatment agent, cerebrovascular disorder treatment agent, retina oxidative disorder inhibitor and lipoxygenase inhibitor that contain the antioxidant.

Diamine derivative, production process therefor and antioxidant

The present invention is directed to compounds represented by the formula (1): B-D-Z (1), wherein B represent the following formula (B-1), (B-2) or (B-3);  

Phenylazole compounds production process and antioxidants

Thienopyrimidine compounds and salts thereof and process for the preparation of the same

Phenylazole compounds represented by general formula (1) or pharmaceutically acceptable salts thereof and drugs for hyperlipemia which contain these compounds as the active ingredient, wherein A represents imidazolyl, pyrazolyl, etc.; B represents (1 ) or (1 ) (wherein R and R represent each hydrogen, C alkyl, etc; and k is 0 or an integer of 1 to 15); Y represents O, S, a bond, etc.; and Z represents an optionally substituted and saturated or unsaturated heterocycle containing 1 to 4 N, O or S atoms. Among all, compounds wherein Z is substituted chroman-2-yl, 2,3-dihydrobenzofuran-2-yl, etc. have an effect of inhibiting the formation of lipid peroxides too.

Phenylazole compounds, process for producing the same and drugs for hyperlipemia

N-substituted imidazol derivative

Optically active compound

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Odawara, Japan

Seiichi Uchida