Otsuka Pharmaceutical Company, Limited

Seiichi Shimizu

Shigeto Uchiyama

Kyosuke Masaki

Tomomi Ueno

Masamichi Toba

Megumi Kumemura

Kiyoko Imaizumi

Shuichi Sakamoto

Reiko Ohta

Takuma Imada

Tsuneyuki Noda

Tatsuya Doi

Koji Okamura

Yasuyuki Yoshioka

This invention provides a composition comprising a daidzein-containing substrate and a strain of micro-organism capable of metabolizing daidzein to equol as essential ingredients. This composition is effective in the prevention and alleviation of unidentified clinical syndrome inclusive of menopausal syndrome in middle-aged to elderly women for which no effective means of prevention or alleviation has heretofore been available.

Isoflavone-containing composition

Microbial method of making equol-containing composition and product made

The antioxidation food product of the present invention is produced by fermenting a food product containing bacteria having catalase activity, such as, in the presence of a manganese-containing natural material. The antioxidation food product has antioxidation activity in viva, including the digestive tract, by simultaneously expressing a superoxide dismutase-like activity and a catalase activity, and is effective for preventing disease caused by active oxygen.

Antioxidation food product, antioxidation preparation and antioxidation method

This invention provides a composition comprising a daidzein-containing substrate and a strain of micro-organism capable of metabolizing daidzein to equol as essential ingredients. This composition is effective in the prevention and alleviation of unidentified clinical syndrome inclusive of menopausal syndrome in middle-aged to elderly woman for which no effective means of prevention or alleviation has heretofore been available.

Streptococcus and isoflavone-containing composition

A method of inhibiting liver fat accumulation which comprises administering a conjugated linoleic acid homolog to a mammal or making the mammal ingest it; and a liver fat accumulation inhibitory composition characterized by containing an effective amount of a conjugated linoleic acid homolog together with a support for medicinal preparations or foods. The administration or ingestion of CLA inhibits the total lipid content and the triglyceride content in the liver from increasing, and hence can effectively prevent diseases attributable to fatty liver, such as chronic hepatitis and hepatic cirrhosis.

Liver fat accumulation inhibitory composition, food additive for liver fat accumulation, inhibition, and method of inhibiting liver fat accumulation

The antioxidation food product of the present invention is produced by fermenting a food product containing bacteria having catalase activity, such as,, in the presence of a manganese-containing natural material. The antioxidation food product has antioxidation activity in vivo, including the digestive tract, by simultaneously expressing a superoxide dismutase-like activity and a catalase activity, and is effective for preventing diseases caused by active oxygen.

Method of producing fermented milk containing manganese and tea

Body fat percent-lowering, body composition-improving food composition

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Tosu, Japan

Seiichi Shimizu