Kanebo, Limited

Seiichi Iwamoto

Shintaro Inoue

Mikio Sotomura

Hiroshi Ohmoto

Akira Suzuki

Isamu Utsumi

Hiroshi Tanaka

Yoshiaki Ikeda

Norimasa Takamatsu

Teruo Sawada

Anti-procollagenase monoclonal antibodies and a method for the assay of

An anti-human papillomavirus (HPV) monoclonal antibody reactive with various types of HPVs, which is produced by a hybridoma comprising a fused cell of a mouse spleen cell from a mouse immunized with an alkali-treated HPV type 1 (HPV-1) and a mouse myeloma cell, and which is reactive with polypeptides of about 57 kilodaltons, about 160 kilodaltons and about 230 kilodaltons of HPV-1, and a process for preparing the same. The monoclonal antibody of the invention is reactive with various types of HPV and useful for diagnosis of various types of HPV infection (primary diagnosis).

Anti-human papillomavirus monoclonal antibody, hybridoma producing the

A process for production of an anti-tumor agent which comprises subjecting the culture cells of the strains belonging to Streptococcus pyogenes in sequence to pasteurization treatment (the first step) and penicillin treatment (the second step), followed by a primary lyophilization (the third step) to obtain an intermediary preparation, and then subjecting the intermediary preparation to penicillin removal treatment (the fourth step), followed by a secondary lyophilization (the fifth step).

Method for the treatment of cells of Streptococcus pyogenes

A process for cultivation of Streptococcus pyogenes comprising cultivating Streptococcus pyogenes in a culture medium for multiplication of bacterial cells having an anti-tumor activity, characterized by (A) using the culture medium containing fermentable carbon sources and (B) maintaining pH of the culture medium at 5.6 or more during the course of cultivation.

Process for cultivation of hemolytic Streptococcus pyogenes

Growing community of inventors

Kobe, Japan

Seiichi Iwamoto