Nipro Corporation

Seigo Kobira

Kazuyoshi Harada

There is provided a solid pharmaceutical preparation for dialysis consisting of one composition, which is excellent in uniformity of the ingredients contained therein, is capable of preventing not only a reaction between sodium bicarbonate and a solid organic acid or between sodium bicarbonate and electrolytes but also a reaction between a solid organic acid and sodium acetate, and does not require further pulverization of the respective ingredients in the dialysis composition. The solid pharmaceutical preparation for dialysis containing an electrolyte for hemodialysis, a solid organic acid and glucose is characterized by a plurality of layers separated from each other on the surface of a nucleating particle of sodium chloride, wherein the plurality of separated layers include a layer (A) comprising sodium acetate but not containing the solid organic acid, a layer (B) comprising the solid organic acid but not containing sodium acetate, and a layer (C) comprising sodium bicarbonate.

Growing community of inventors

Osaka, Japan

Seigo Kobira