Diadexus, Inc.

Sei-Yu Chen

Yongming Sun

Herve Recipon

Roberto A Macina

Chenghua Liu

Leah R Turner

The present invention provides new methods for detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating cancer.

Method of diagnosing, monitoring, staging, imaging and treating cancer

Method of diagnosing monitoring, staging, imaging and treating cancer

The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic lung cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating lung cancer and non-cancerous disease states in lung, identifying lung tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered lung tissue for treatment and research.

Compositions and methods relating to lung specific genes and proteins

Growing community of inventors

Foster City, CA, United States of America

Sei-Yu Chen