Siemens Healthcare Diagnostics Gmbh

Seema Sinha

Niver Panosian Sahakian

Prakash Tewari

Haekyung Lee

Gabriel Hammarquist

Saji Cherian

Aili Han

Kuldeep Jaggi

Paul D'Agostino

Kayla Cortese

Maral Poladian

Robert J Owens

Spencer Lin

Ryan Spears

Kwasi Osae-Kwapong

Omar Quraishi

Michele Smith

SunRay DiFrancesco

Dharini Rawal

Debra Hovanec-Burns

Tom Chuang

Tramanh Tran

Jelena Bogdanovic

Agata Jacewicz

A human insulin-like growth factor (IGF) binding protein stock solution and method of making the same include a non-recombinant human IGF binding protein-3 (nr-IGFBP-3) in an aqueous buffered medium. The concentration of the nr-IGFBP-3 in the stock solution ranges from about 16 micrograms per milliliter (μg/ml) to about 40 μg/ml. A kit includes a set of calibrators for nr-IGFBP-3. The set of calibrators includes the nr-IGFBP-3 in different concentrations.

Non-recombinant human insulin-like growth factor binding protein concentrate

Disclosed herein are immunoassays for detecting an anti-thyroid peroxidase antibody in a biological sample from a subject and/or diagnosing a thyroid disease in a subject. The disclosed immunoassays employ a recombinant cynomolgus monkey thyroid peroxidase (rTPO) and assess the level of anti-thyroid peroxidase antibody-induced formation or disruption of complexes comprising a solid support and the rTPO.

Thyroid peroxidase autoantibody immunoassay

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Rancho Santa Margarita, CA, United States of America

Seema Sinha