Sofradim Production

Covidien LP

Centre National De La Recherche Scientifique

Tyco Healthcare Group LP

Université Claude Bernard Lyon I

Codivien LP

Sébastien Ladet

Philippe Gravagna

Yves Bayon

Sebastien Francois

Ahmad Robert Hadba

Olivier Lefranc

Nicolas Prost

Julie Lecuivre

Robert Vestberg

Alain Domard

Julien Claret

Jack Kennedy

Muriel Guerin

Maud Buffin

Christophe Viton

Sébastien Francois

Sébastien François

Prosthesis () comprising a patch () made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a centre, a length and a width of said patch, characterized in that said patch is provided, on one () of its faces, with a single marking means () designed to indicate both the centre (C) of the patch and also the longitudinal direction of said patch.

Hernia prosthesis with marking means

The invention relates to a device () and method for selecting the size and shape of a prosthesis and/or for determining the location of marks to be made on the external face of the skin of a patient intended to receive such a prosthesis, for example for repairing a hernia, comprising a sheet () of transparent material, the said sheet comprising: &#x2014;a plurality of graphical representations () concentrically embodying the respective outlines of various shapes and sizes of prosthesis, &#x2014;a plurality of first holes () arranged along the transverse line passing through the centre of the said sheet, and &#x2014;a plurality of second holes () arranged along the longitudinal line passing through the centre (C) of the said sheet.

Guide for selecting and positioning a prosthesis

The present disclosure relates to compounds and medical devices activated with a solvophobic material functionalized with a first reactive member and methods of making such compounds and devices.

Compounds and medical devices activated with solvophobic linkers

Mono- and multi-layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.

Implant for tissue repair including chitosan

Method for preparing a chitosan-based porous layer The present invention relates to a method or preparing a chitosan-based, neutralized compressed porous layer, comprising the following steps: &#x2014;a) a chitosan solution is prepared, &#x2014;b) said solution is poured into a mold in order to form a layer, &#x2014;c) the layer obtained in b) is lyophilized so as to obtain a porous layer, &#x2014;d) said porous layer obtained in c) is compressed, &#x2014;e) the compressed porous layer obtained in d) is neutralized by means of an NHOH solution. It also relates to an implant comprising a layer obtained according to such a method.

Method for preparing a chitosan-based porous layer

The present invention relates to a process for preparing a porous layer of biocompatible polymer, having a uniform density and porosity, comprising the following steps:

Process for preparing a porous layer

A method for closing a wound in tissue is provided which includes providing a surgical fastener having a plurality of reactive members of a specific binding pair attached on a surface of the surgical fastener, and providing tissue with a plurality of complementary reactive members of the specific binding pair, wherein upon contact of the reactive members on the surface of the surgical fastener with the complimentary reactive members on the tissue, covalent bonds are formed between the reactive members and the complementary reactive members, thus adhering the device to the tissue.

Surgical fasteners and methods for sealing wounds

The invention relates to a device () and method for selecting the size and shape of a prosthesis and/or for determining the location of marks to be made on the external face of the skin of a patient intended to receive such a prosthesis, for example for repairing a hernia, comprising a sheet () of transparent material, the said sheet comprising: &#x2014;a plurality of graphical representations () concentrically embodying the respective outlines of various shapes and sizes of prosthesis, &#x2014;a plurality of first holes () arranged along the transverse line passing through the center of the said sheet, and&#x2014;a plurality of second holes () arranged along the longitudinal line passing through the center (C) of the said sheet.

A method for bonding a polymeric fiber to tissue is provided which includes providing a polymeric fiber having a plurality of tissue reactive members linked to a surface of the fiber via a specific binding pair, and contacting the polymeric fiber to biological tissue, to covalently bond the fiber to the tissue.

Polymeric fibers having tissue reactive members

Mono- and multi- layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.

Prosthesis () comprising a patch () made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a center, a length and a width of said patch, characterized in that said patch is provided, on one () of its faces, with a single marking means () designed to indicate both the center (C) of the patch and also the longitudinal direction of said patch.

Enzymatically degradable compositions containing biocompatible polymers reactive with glycosaminoglycan compositions having a first glycosaminoglycan having a first degree of acetylation and a second glycosaminoglycan having a second degree acetylation different than the first degree of acetylation.

Multilayer implants for delivery of therapeutic agents

Implants for tissue repair/regeneration include a porous layer combined with dry materials that are activated to form a hydrogel upon contact with aqueous physiological fluids.

Auto-sealant matrix for tissue repair

The present invention relates to a prosthesis () comprising:&#x2014;at least one layer of a flexible mesh () delimited by a peripheral outer edge (), said mesh having a first color, and&#x2014;at least one layer () of porous material fixed to said mesh substantially along the perimeter of said peripheral outer edge, said layer of porous material being recessed at its central part (), said layer of porous material having a second color, different from said first color.

Growing community of inventors

Lyons, France

Sébastien Ladet