Aker Biomarine Antarctic as

Aker Biomarine Antartic as

Aker Biomarine as

Universitá Degli Studi Di Cagliari

Bunge Loders Croklaan B.v.

Aker Biomarine Asa

Sofedus S.r.l.

Sebastiano Banni

Inge Bruheim

Mikko Griinari

Daniele Mancinelli

Snorre Tilseth

Nils Hoem

Per Christian Saebo

Jeffery Cohn

Erik Fuglseth

Hogne Vik

Jeffrey Stuart Cohn

Jeffrey Cohn

Anna Petroni

Marco Cappa

Miriam Melis

Marco Pistis

Valeria Sogos

Luisa Gambelli

Randolph Happe

Novel marine lipid compositions comprising triglycerides and omega-3 rich phospholipids are described. The compositions are characterized by providing highly bioavailable omega-3, increased tissue incorporation of omega-3 and reduced concentration of pro-inflammatory cytokines.

Anti-inflammatory properties of marine lipid compositions

This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondria respiratory chain. The present invention further includes pharmaceutical and/or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. Further, a method of reducing appetite in humans by administering a krill oil composition is also disclosed.

Method of reducing appetite in a human subject comprising administering krill oil composition

This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondria respiratory chain. The present invention further includes pharmaceutical and/or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders.

Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders

This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical COor COplus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical COin combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.

Bioeffective krill oil compositions

This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondrial respiratory chain. The present invention further includes pharmaceutical and/or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders.

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Cagliari, Italy

Sebastiano Banni