Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V.

Washington University

Sebastian Ulbert

Christiane Wetzel

Daved Henry Fremont

Michael S Diamond

Jessy Schönfelder

Frank-Holm Rögner

Javier Portillo

Mathias Salomo

Stefan Chabierski

Matthias Giese

Jana Burkhardt

Alexandra Rockstroh

Samiya Al-Robaiy

N Delaroque

The present invention relates to a method for irradiating a population of mammalian cells comprising at least one target mammalian cell with electron beams and/or X-rays, characterized in that: (i) a composition comprising a population of mammalian cells is irradiated in vitro with electron beams and/or X-rays, the population of mammalian cells containing at least one target mammalian cell and the dose rate being within the range from 5 Gy/sec to 10Gy/sec, and (ii) optionally viable target mammalian cells are isolated or enriched from the population of mammalian cells, and to agents obtainable thereby and to uses thereof.

Method for irradiating mammalian cells with electron beams and/or X-rays

The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.

Method for inactivating viruses using electron beams

The present invention relates to mutant peptides of the E protein of the West Nile virus and other flaviviruses useful for discriminating flaviviral infections, as well as kits, methods and uses related thereto.

Distinguishing flavivirus infection using a recombinant mutant envelope protein

Growing community of inventors

Leipzig, Germany

Sebastian Ulbert