Grunenthal Gmbh

Gruenenthal Gmbh

Sebastian Schwier

Lutz Barnscheid

Klaus Wening

Jana Pätz

Johannes Bartholomäus

Johannes Heinrich Bartholomaeus

Eric Galia

Ulrike Bertram

Marcel Haupts

Anja Geissler

Anja Geißler

Kornelia Griessmann

Anja Geiβler

Jessica Redmer

Jana Denker

Udo Rüttgers

Julia Baronsky-Probst

Stefanie Strauch

The invention relates to a tamper-resistant tablet comprising

Tamper-resistant tablet providing immediate drug release

The invention relates to a pharmaceutical dosage form which is particularly useful for the prevention of an overdose of the pharmacologically active ingredient contained therein after accidental or intentional simultaneous administration of a plurality of the dosage forms containing an overall supratherapeutic dose of the pharmacologically active ingredient.

Protecting oral overdose with abuse deterrent immediate release formulations

The invention relates to a tamper-resistant, oral pharmaceutical dosage form comprising a pharmacologically active ingredient having psychotropic action and an ethylene-vinyl acetate (EVA) polymer which provides resistance against solvent extraction, resistance against grinding, and resistance against dose-dumping in aqueous ethanol.

Tamper-resistant dosage form containing ethylene-vinyl acetate polymer

A thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising

Oxidation-stabilized tamper-resistant dosage form

A tamper-resistant pharmaceutical dosage form comprising a pharmacologically active ingredient embedded in a prolonged release matrix, which comprises a prolonged release matrix material selected from the group consisting of nonionic acrylic polymers and waxy materials and which provides prolonged release of the pharmacologically active ingredient, resistance against solvent extraction, resistance against grinding, and resistance against dose-dumping in aqueous ethanol.

Tamper resistant and dose-dumping resistant pharmaceutical dosage form

A thermoformed, tamper-resistant pharmaceutical dosage form comprises: When the pharmacologically active ingredient is effective against pain, the pharmaceutical dosage form may be used in a method of treating pain. When the pharmacologically active ingredient has abuse potential, the pharmaceutical dosage form may be used in a method of reducing the incidence of the abuse of said pharmacologically active ingredient.

Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc

The invention relates to a pharmaceutical dosage form comprising

Tamper resistant dosage form with bimodal release profile

The invention relates to a pharmaceutical dosage form having a breaking strength of at least 300 N and comprising a pharmacologically active compound, an anionic polymer bearing carboxylic groups, wherein the content of the anionic polymer is &#x2267;20 wt.-%, based on the total weight of the pharmaceutical dosage form, and a nonionic surfactant.

Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer

A pharmaceutical dosage form and method of using same, the pharmaceutical dosage form exhibiting a breaking strength of at least 500 N, said dosage form containing

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Aachen, Germany

Sebastian Schwier