Dexcom, Inc.

Illumina Corporation

Alcon Research, Ltd.

Sebastian Bohm

Peter C Simpson

Mark Dervaes

Daiting Rong

Phong Lieu

Jack Pryor

Paul V Neale

Jacob S Leach

Shawn Larvenz

Matthew D Wightlin

Robert James Boock

Disha B Sheth

Thomas Miller

Jason M Halac

Jason Mitchell

Jennifer Blackwell

Vincent Peter Crabtree

Michael J Estes

Apurv Ullas Kamath

Aarthi Mahalingam

Thomas Arnold Peyser

Jeff Jackson

Todd Andrew Newhouse

Michael A Ploof

Minglian Shi

Michael Levozier Moore

Stephen Alan Reichert

Sean T Saint

Nicholas Kalfas

Shanger Wang

Douglas William Burnette

Tom Miller

David DeRenzy

Kenneth San Vicente

Eric Johnson

Mohammad Ali Shariati

Jiong Zou

Wenjie Lan

Tarun Kumar Khurana

Antonio C Llevares

Kaushik Aroonkumar Patel

Rui Ma

Zebediah L McDaniel

Anna Claire Harley-Trochimczyk

Alexander Leroy Teeter

Thomas George O'Connell

Brian Christopher Smith

Ryan Everett Schoonmaker

Dale Buermann

John Michael Gray

Ted Tang Lee

Benjamin Elrod West

Maria Noel Brown Wells

Neel Narayan Shah

William Anthony Pender

James Stephen Amidei

Alexander Hsiao

James H Brauker

Michael Robert Mensinger

Eli Reihman

Katherine Yerre Koehler

Eric Cohen

Hari Hampapuram

Helmy A Eltoukhy

Leif N Bowman

Boyan Boyanov

M Shane Bowen

Daniel Steven Kline

Naresh Chandra Bhavaraju

Robert C Kain

Arturo Garcia

Stephen J Vanslyke

Phil Mayou

Min-Jui Richard Shen

Hai Quang Tran

Steve Masterson

Alex Aravanis

Leslie Ann Field

David A Keller

Jian Gong

Arash Jamshidi

Majid Aghababazadeh

Becky L Clark

AmirAli Talasaz

Andrew Michael Reinhardt

Rodolfo Garcia

Jaroslaw Piotrowiak

Arlene G Doria

John Patrick Majewski

Leah Morta Edra

Behnam Javanmardi

Eric Hans Vermaas

Antonio Ubach

Anna Leigh Rack-Gomer

Kenneth M Kuhn

Kamuran Turksoy

Liang Wang

Lucas Bohnett

Adam J Livingston

Huashi Zhang

This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.

Systems, devices, and methods to compensate for temperature effects on sensors

Various analyte sensor systems for controlling activation of analyte sensor electronics circuitry are provided. Related methods for controlling analyte sensor electronics circuitry are also provided. Various analyte sensor systems for monitoring an analyte in a host are also provided. Various circuits for controlling activation of an analyte sensor system are also provided. Analyte sensor systems utilizing a state machine having a plurality of states for collecting a plurality of digital counts and waking a controller responsive to a wake up signal are also provided. Related methods for such analyte sensor systems are also provided. Systems for controlling activation of analyte sensor electronics circuitry utilizing a magnetic sensor are further provided. One or more display device configured to display one or more analyte concentration values are also provided.

Systems and method for activating analyte sensor electronics

Various examples described herein are directed to systems and methods for determining an analyte concentration using an analyte sensor. A method may comprise disconnecting an analyte sensor from a measurement circuit and reconnecting the analyte sensor to the measurement circuit after an accumulation period. The method may comprise receiving a signal from the analyte sensor. The signal may be indicative of an amount of charge accumulated on the analyte sensor during the accumulation period. The method may also comprise determining an estimated analyte concentration level based on the received signal.

Analyte sensor with impedance determination

Systems, methods, apparatuses, and devices, for the wireless communication of analyte data are provided. In some embodiments, a method and calibration station for calibrating a continuous analyte sensor system is provided. Methods and testing systems for testing a continuous analyte sensor system is provided. Continuous analyte sensor systems, display devices and peripheral devices configured for wireless communication of analyte, connection, alarm and/or alert data and associated methods are provided.

System and method for wireless communication of analyte data

The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid. The continuous analyte sensor can be physically connected to a sensor electronics module, which is in direct wireless communication with a plurality of different display devices.

Advanced continuous analyte monitoring system

Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor systemcomprising two working electrodes and at least one reference/counter electrode is provided. The sensor systemcomprises first and second elongated bodies E, E, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layerthat separates the conductive layerfrom the elongated body, a membrane layer deposited on top of the elongated bodies E, E, and working electrodes″ formed by removing portions of the conductive layerand the insulating layer, thereby exposing electroactive surface of the elongated bodies E, E

Analyte sensors and methods of manufacturing same

Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises activating a transceiver of a first communication device associated with an analyte sensor at a first time. The method also includes establishing a two-way communication channel with the second communication device. The activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device.

Systems and methods for processing and transmitting sensor data

Various examples are directed to systems and methods for operating an analyte sensor system using sensor electronics. An example method may comprise applying a bias voltage change to an analyte sensor bias voltage and measuring a current value for each of a plurality of time periods after application of the bias voltage change. The example method may also comprise determining an estimated impedance using the current values for the plurality of time periods and determining a characteristic of the analyte sensor using the estimated impedance. The example method may further comprise receiving from the analyte sensor a signal indicative of an analyte concentration, and determining an estimated analyte concentration level using the determined characteristic of the analyte sensor and the received signal.

Sensor devices including dissolvable tissue-piercing tips are provided. Methods of using and fabricating sensor devices are also provided.

Sensors for continuous analyte monitoring

Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device.

Various examples are directed to systems and methods of and using analyte sensors. An example analyte sensor system comprises an analyte sensor and a hardware device in communication with the analyte sensor. The hardware device may be configured to perform operations comprising applying a first bias voltage to the analyte sensor, the first bias voltage less than an operational bias voltage of the analyte sensor, measuring a first current at the analyte sensor when the first bias voltage is applied, and applying a second bias voltage to the analyte sensor. The operations may further comprise measuring a second current at the analyte sensor when the second bias voltage is applied, detecting a plateau bias voltage using the first current and the second current, determining that the plateau bias voltage is less than a plateau bias voltage threshold, and executing a responsive action at the analyte sensor.

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San Diego, CA, United States of America

Sebastian Bohm