Council of Scientific and Industrial Research

Seayad A Majeed

Raghunath Vitthal Chaudhari

Jayasree Seayad

The present invention relates to an process for the preparation of ibuprofen, which comprises reacting para isobutyl phenylethanol (p-IBPE), a halide source, a protonic acid, water and the catalyst which is a compound having formula 1 which is shown herebelow: ##STR1## Wherein M = a group VIII metal specifically palladium or platinum,

Process for the preparation of ibuprofen

The present invention relates to novel group VIII transition metal complexes represented by the formula (I) as: ##STR1## wherein M is the central transition metal; represents a semilabile anionic chelating ligand; R.sub.1, R.sub.2 & R.sub.3 are substituents on the phosphine ligand, X is chosen from sulphonato, carboxylato, formato group or halides and 1&lt;n&lt;10. The invention also provides a process for the preparation of said transition metal complex.

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Maharashtra, India

Seayad A Majeed