Depuy Synthes Products, Inc.

Synthes USA, LLC

Synthes Gmbh

Other

Medos International Sarl

Depuy Spine, Inc.

Sean Hamilton Kerr

James Dwyer

Ali Cem Recber

David A Armbruster

Mark T Fulmer

Lawton Laurence

Dominique D Messerli

Thomas Kueenzi

Ryan T Walsh

Thomas Pepe

Brandon L Randall

Michael Lehmicke

Junior Julien

Bryan Monro Armitage

Robert Frigg

Elliott A Gruskin

Ira C Ison

Jeffrey S Chomyn

Christopher Shane

Patrick Leamy

William Schiffer

Edward August Kurek, Iii

James P Hearn

James Velikaris

John H Manthorp

Joern Richter

Thomas J Gamache

J Riley Hawkins

Ross Hamel

Jeffrey A McAnelly

Rodney E Satterthwaite

Jay Smith

Jeff Kiersh

John Maurice Marthaler

Kortney Wawrzyniak

Elliot A Gruskin

Ami Saheba Joshi

Steven Paul Parmelee

Ed Kurek

Christopher Michael Magee

Timothy P Moses

Ali Cern Recber

Ami Saheba

Urs Wigger

Paul Burns

Peter Kurzyna

Meredith Hans Moore

David Armbruster

James W Dwyer

Ross J Hamel

Demitrios Velikaris

Jeffrey Chomyn

Brian Monroe Armitage

Ira Ison

Jeffrey A Mcanelly

Ryan Walsh

Randall Brandon

Ali Recber

Mark Thomas Fulmer

James (deceased) Dwyer

Embodiments described include devices and methods for forming a porous polymer material. Devices disclosed and formed using the methods described a spacer for spinal fusion, craniomaxillofacial (CMF) structures, and other structures for tissue implants.

Porous biocompatible polymer material and methods

Inflatable orthopedic implants and related methods are disclosed herein, e.g., for deploying such implants within an intervertebral space for use in spinal fusion surgery, other intervertebral surgical procedures, or other surgical procedures. The inflatable intervertebral implant can include a hollow inflatable body that can be configured in a compact state for insertion into a target intervertebral space between a pair of adjacent vertebral bodies. Once the vertebral bodies are separated or distracted, e.g., using one or more inflatable distractors, the hollow body of the inflatable implant can be inflated with bone cement or other curable material. When the curable material hardens, the inflated implant can form a rigid intervertebral support structure (e.g., a fusion cage) capable of maintaining the vertebral distraction and thereby enabling removal of the distractors.

Inflatable non-distracting intervertebral implants and related methods

A method for augmenting a tissue including introducing into the tissue a first thermoplastic material at a first condition; treating the first thermoplastic material to achieve a second condition that includes an at least partially crystalline skin; and introducing a second material into the tissue whereby the first thermoplastic material and the second material are contained by the at least partially crystalline skin. Also a method of fracture reduction in a tissue including exposing to gamma radiation a mass of polycaprolactone characterized by a first shape; heating the mass of irradiated polycaprolactone above its melting temperature; introducing the heated mass of polycaprolactone into the tissue annulus to deform it from the first shape; allowing the material to return to the first shape.

Methods of augmenting, reducing, and repairing bone with thermoplastic materials

A drug-impregnated sleeve for encasing a medical implant is provided. In one embodiment, the sleeve may include a body made of a biologically-compatible material that defines an internal cavity configured to receive the medical implant. In one embodiment, the biologically-compatible material is bioresorbable. The body may include a plurality of apertures, such as perforations or holes, extending from the cavity through the body. The sleeve may further include a first end, a second end, and a drug impregnated into the resorbable sheet. In one possible embodiment, the first end of the sleeve may be open for receiving the medical implant therethrough and the second end may be closed. The implant may be encased in the sleeve and implanted into a patient from which the drug is dispensed in vivo over time to tissue surrounding the implantation site. In one embodiment, the body is made from at least one sheet of a biologically-compatible material.

Drug-impregnated encasement

A first tool is configured to cut a polymer implant, and includes a handle, a cutting portion, and a bending portion. A second tool is configured to cut a polymer implant, and includes a handle, a first cutting portion, and a second cutting portion. The cutting portions contain a cutter that is preferably a blade. In the second tool, the blades are preferably angled with respect to each other between about 45&#xb0;. The tools can be used to reshape an implant that is to be used to replace a portion of a skull.

Cutting/bending tool for polymer implant

A system for reaming a medullary canal of a bone, comprises a reamer device including an elongated member and a reamer head rotatably coupled to a distal end of the elongated member and a drive shaft sized and shaped to be inserted through the elongated member so that a first connector at a distal end of the drive shaft is engagable with the reamer head, rotation of the drive shaft rotates the reamer head relative to the elongated member, the drive shaft including a channel extending longitudinally therethrough and a hole extending laterally therethrough from a first opening through a first side wall of the drive shaft to a second opening through a second side wall of the drive shaft in combination with a seal configured to be inserted through the hole of the drive shaft so that the seal extends across the channel of the drive shaft.

Guide wire seal for reamer irrigator aspirator system

A flexible body comprises a polymer film having a first surface and an opposing second surface. The polymer film has a plurality of apertures extending from the first surface to the second surface and a plurality of raised lips protruding from the first surface such that each of the plurality of apertures is surrounded by one of the plurality of raised lips. A method of producing a polymer film comprises placing a polymer solution into a one sided mold having a plurality of protrusions extending from a bottom of the mold wherein the polymer solution is characterized by a viscosity that inhibits the unaided flow of the polymer throughout the mold; urging the polymer solution around each of the plurality of protrusions; and solidifying the polymer solution.

Films and methods of manufacture

Provided are porous, biocompatible implant bodies and materials. These materials suitably comprise a population of randomly arranged and entangled thermoplastic constituents, with at least some of the constituents being bonded to one another. The implant bodies are capable of being manipulated at room temperature from a first shape to a second shape, and of maintaining the second shape at about internal body temperature. Also provided are related methods of fabricating such implants and installing the implants into a subject.

Porous implant materials and related methods

Embodiments of the present disclosure are directed to perforated polymer films and methods of making the same. In some embodiments, the films are for use with implantable medical devices. In one embodiment there is a flexible body including a polymer film having a first surface and an opposing second surface, the film having a plurality of apertures extending from the first surface to the second surface and a plurality of raised lips protruding from the first surface such that each of the plurality of apertures is surrounded by a one of the plurality of raised lips. In one embodiment, the film comprises a single layer, and in another embodiment, the film can comprise a plurality of layers. In certain embodiments, the film can comprise an adhesive layer. In another embodiment, one or more of the layers may be a drug containing layer and/or a rate controlling layer for drug release.

A modular femoral prosthesis system for an orthopedic hip implant and method of use is disclosed. The prosthesis system includes a femoral stem component and a plurality of collar components configured to be selectively coupled to the stem component in a fixed position adjacent to a neck of the stem component. Each of the collar components includes a base and is configured to secure an assembled femoral prosthesis to a patient's surgically prepared femur to provide stability for the assembled femoral prosthesis.

Modular femoral prosthesis system for hip arthroplasty

Provided are porous, biocompatible implant bodies and materials. These materials suitably comprise a population of randomly arranged and entangled thermoplastic constituents, with at least some of the constituents being bonded to one another The implant bodies are capable of being manipulated at room temperature from a first shape to a second shape, and of maintaining the second shape at about internal body temperature. Also provided are related methods of fabricating such implants and installing the implants into a subject.

Methods and devices are shown for forming polymer fasteners into bone by expelling the polymer from a cannula. Devices and methods shown allow a user to form multiple fasteners of various sizes without re-loading a device. Devices and methods shown further provide temperature profiles during fastener formation that reduce or eliminate thermal necrosis. Devices and methods shown further provide fasteners with increased strength.

Injectable fastener system and method

Method for augmenting, reducing, and repairing bone with thermoplastic materials

Growing community of inventors

Oreland, PA, United States of America

Sean Hamilton Kerr