Arizona State University

Sean Buizer

Deirdre Meldrum

Yanqing Tian

Fengyu Su

Liqiang Zhang

Laimonas Kelbauskas

Clifford Anderson

Kristen Lee

The present disclosure relates to an optical fluorescence sensor comprising a probe for sensing glucose, an intra-reference probe, and a matrix. The present disclosure also relates to an optical fluorescence dual sensor comprising a probe for sensing glucose having two boronic acid moieties, a probe for sensing oxygen comprising modified porphyrin, an intra-reference probe that is rhodamine-based, and a matrix. The present disclosure additionally relates to methods of preparing these sensors and methods of using them.

Tri-color dual glucose and oxygen sensors and methods of preparing and using them

A triple sensor structured for simultaneous measurement of glucose, oxygen, and pH. The sensor components are in thin film states such as sensing films or membranes, with a glucose probe associated with emission of radiation in the blue part of the spectrum, an oxygen probe associated with radiation in red portion of the spectrum, and a pH probe&#x2014;with a green portion of the spectrum. The optical probes are chemically grafted or immobilized in a suitable polymer matrix, alleviating the leaching of the probes from the matrix, improving the thin film sensing stability, and enabling the repeatable use of the same sensing films.

Cellarium: thin-film sensor with microarray seal

Growing community of inventors

Tempe, AZ, United States of America

Sean Buizer