Oscotec Inc.

Samsung Electronics Co., Ltd.

Korea Research Institute of Chemical Technology

Yuhan Corporation

Genosco

Oscotech Inc.

Se-Won Kim

Jung-Keun Kim

Seon-Yle Ko

Jaekyoo Lee

Jung-Ho Kim

Dong-Heon Baek

Hyung-Gun Kim

Jong Sung Koh

Ho-Juhn Song

Jang-Sik Choi

Dong-Sik Jung

In Y Lee

Byung-Chul Suh

Paresh Salgaonkar

Dong Sik Jung

Jaesang Lee

Sunhwa Chang

Hyuk Jae Lee

Jung Nyoung Heo

Yeon Soo Lee

Jung-ho Kim

Young-Kwon Yoon

Kyung Hoon Kim

Jun-Young Park

Doo-Sik Shin

Byung-sun Choi

Bum Tae Kim

Yong Ki Min

Hee Kyu Lee

No Kyun Park

Sung-Ho Park

Yung-Geun Choi

Jong-Sung Koh

Song-Eun Park

Il Yong Cho

Byoung Guk Lim

Hong Woo Kim

Hyung-Jin Rho

Hyun-Ho Yu

Young-Bok Yu

Yeon-Ju Lee

Sun-Hee Lim

Youngsam Kim

Hae-Jun Hwang

Dong-Ik Jang

Se-Nyum Kim

Jung Ho Kim

Dae-Pil Kang

Hwa Sil Kim

Youn Ho Han

Guo Fan Jin

Ji Min Kim

Youngnim Choi

Seong-Hee Ko

Byung-Eui Lee

Jong-Yeo Kim

Jhi Zheng

Tae-Im Lee

Dong-Hun Yu

Heejong Woo

Hyung-Gun 5-108 Jinheung Apt Kim

Jung-Keun 114-302 Hyundai Apt Kim

Hyuk; Lee

Jung-Keun Hyojachon Hyundai Apt 114-302 Kim

Seong-Hee 101-802 Cheongsong Apt Ko

Heejong 306-1807 Hyangchonhyundai Apt Woo

Byung-Eui 102-106 Life Saeyeoul Apt Lee

Youngnim College Of Dentistry Choi

Paresh Devidas Salgaonkar

In Yong Lee

The present invention provides a new group of protein kinase inhibitors, aminopyrimidine derivatives, and pharmaceutically acceptable salts thereof that are useful for treating cell proliferative disease and disorder such as cancer and immune disease. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefore. The invention also provides useful intermediates generated during the syntheses of the aminopyrimidine derivatives.

Compounds and compositions for modulating EGFR mutant kinase activities

An embodiment relates to a crystal polymorph of 8-bromo-2-(1-methylpiperidin-4-ylamino)-4-(4-phenoxyphenylamino)pyrido [4,3-d]pyrimidin-5(6H)-one hydrochloride which can effectively suppress FLT3 and has excellent stability even in a high temperature and humid environment, and a method for preparing same.

Crystal polymorph of 8-bromo-2-(1-methylpiperidin-4-ylamino)-4-(4-phenoxyphenylamino)pyrido[4,3-d]pyrimidin-5(6H)-one hydrochloride and method for preparing same

A pyrrolo(pyrazolo)pyrimidine compound of Formula 1, a pharmaceutically acceptable salt, a hydrate, a solvate, a prodrug, and an isomer, and pharmaceutical compositions containing the compound are disclosed. The compound of Formula 1 shows excellent LRRK2 inhibitory activity. Method for manufacturing the compound and uses thereof as an LRRK2 inhibitor and methods for treating or preventing degenerative brain diseases employing the compound are disclosed: 

Substituted pyrazoles as LRRK2 inhibitors

A camera module according to various embodiments of the present invention comprises: a fixed part; a movable part for receiving a lens assembly, the movable part being coupled to the fixed part to be movable in a plane perpendicular to an optic axis of the lens assembly; and a guiding part for guiding the movement of the movable part, the guiding part being interposed between the fixed part and the movable part, wherein the guiding part can be formed in a C shape of which at least one side is opened. The camera module as above can be implemented variously according to the embodiments.

Camera module having guiding portion between fixed portion and movable portion

The present disclosure provides an air conditioner. The air conditioner includes a compressor; a sensor for measuring the compressors state configured to detect compressor state information that includes at least one of a pressure value and a saturation temperature of the compressor; and a controller configured to control air flow on the side of an indoor unit by comparing the compressor state information measured from the sensor and a threshold.

Air conditioner and method for controlling the same

Compounds of Formula (I) and methods for inhibiting kinases, including spleen tyrosine kinases, are disclosed. Also disclosed are methods for treating a kinase-mediated disease or condition by administering to a subject a therapeutically effective amount of the compound of Formula (I). 

Substituted pyrimidine compounds and their use as SYK inhibitors

The present invention relates to an alpha-arylmethoxyacrylate derivative, a preparation method thereof and a pharmaceutical composition comprising the same, and the alpha-arylmethoxyacrylate derivative is inhibitory of HIF, which plays an important role in the regulation of genes associated with energy metabolism, vasomotion, angiogenesis and apoptosis and in the response of cells under hypoxic conditions, so that it can be used for preventing or treating of diseases such as cancer, arthritis, psoriasis, diabetic retinopathy and macular degeneration.

Alpha-arylmethoxyacrylate derivative, preparation method thereof, and pharmaceutical composition containing same

The present invention provides a new group of protein kinase inhibitors, pyrropyrimidine and pyrazolopyrimidine derivatives, and pharmaceutically acceptable salts and prodrugs thereof that are useful for treating cell proliferative disease and disorder such as cancer, autoimmune diseases, infection, cardiovascular disease and neurodegenerative disease and disorder. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor. The invention also provides useful intermediates generated during the syntheses of the pyrropyrimidine and pyrazolopyrimidine derivatives.

Kinase inhibitors

The present invention relates to a herbal mixture extract of Rehmanniae Radix Preparata and Acanthopanacis Cortex and a composition comprising the same for the prevention and treatment of osteoporosis. The herbal mixture extract of the present invention enhances the expression of osteoprotegerin (OPG) in osteoblasts and effectively inhibits the generation and activation of osteoclasts, so that it can be effectively used for the prevention and treatment of osteoporosis.

Herbal mixture extract of rehmanniae radix preparata and acanthopanacis cortex and a composition comprising the same for prevention and treatment of osteoporosis

The present invention relates to a use of a specific alpha-arylmethoxyacrylate derivative, or its pharmacologically acceptable salt or solvate for preventing and treating metabolic bone diseases.

Pharmaceutical composition for preventing and treating metabolic bone diseases containing alpha-arylmethoxyacrylate derivatives

The present invention relates to a herbal mixture extract ofPreparata andand a composition comprising the same for the prevention and treatment of osteoporosis. The herbal mixture extract of the present invention enhances the expression of osteoprotegerin (OPG) in osteoblasts and effectively inhibits the generation and activation of osteoclasts, so that it can be effectively used for the prevention and treatment of osteoporosis.

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Pharmaceutical composition for preventing and treating metabolic bone diseases containing alpha-arylmethoxyactylate derivatives

The present invention relates to an extract of an herbal mixture ofand, and a method for treating arthritis using the extract as an effective ingredient. The extract of the herbal mixture of the present invention can effectively inhibits the release of inflammatory substances and the synthesis of cartilage destroying substance as well as the progress of arthritis.

Herbal mixture extract of notoginseng radix, rehmanniae radix preparata and acanthopanacis cortex and composition comprising the same for prevention and treatment of arthritis

The present invention relates to a herbal mixture extract ofandand a composition for prevention and treatment of periodontal disease containing the herbal mixture extract as an active ingredient, more precisely, a herbal mixture extract having activities of inhibiting the generation and activation of osteoclasts by enhancing the expression of osteoprotegerin (OPG) in osteoblasts, preventing alveolar bone from destruction by inhibiting the proliferation of osteoclasts and maintaining the growth of periodontal ligament cells and gingival fibroblasts, and a composition for prevention and treatment of periodontal disease containing the above mixture as an active ingredient.

Growing community of inventors

Cheonan-si, South Korea

Se-Won Kim