Biovest International, Inc.

Scott Waniger

Grant A Adams

Robert J Wojciechowski

Mark Hirschel

Darrell Paul Page

Thiem Chan Duong Wong

Michael J Gramer

Martin Peder Crep

Karl Patrick Bongers

Beverly Norris

Kimberly Arneson

Jeff Jorgensen

A cell culture system for the production of cells and cell derived products includes a reusable instrumentation base device incorporating hardware to support cell culture growth. A disposable cultureware module including a cell growth chamber is removably attachable to the instrumentation base device. The base device includes microprocessor control and a pump for circulating cell culture medium through the cell growth chamber. The cultureware module is removably attached to the instrumentation base device. Cells are introduced into the cell growth chamber and a source of medium is fluidly attached to the cultureware module. Operating parameters are programmed into the microprocessor control. The pump is operated to circulate the medium through the cell growth chamber to grow cells or cell products therein. The grown cells or cell products are harvested from the cell growth chamber and the cultureware module is then disposed.

Method and system for the production of cells and cell products and applications thereof

The subject invention pertains to methods and apparatus for the production and purification of cell products, such as immunoglobulins. One aspect of the invention is an integrated cell culture and purification apparatus for the growth and maintenance of cells and the harvest and purification of cell products, such as immunoglobulins. Thus, the apparatus integrates a cell culture function with a purification function. Other aspects of the invention pertain to an automated method for producing immunogenic compositions such as vaccines.

Method and apparatus for antibody production and purification

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Andover, MN, United States of America

Scott Waniger