University of California

Alessa Therapeutics, Inc.

Healthy.io Ltd

Scott Thomas

Pamela Munster

Keith Hall

Carlos Schuler

Pujan Desai

Maithili Rairkar

John Maroney

Margaret McLaughlin

Maxime Daud

Tobias H Casab

Jim Kiriakis

Maxime D Rappaport

Hani Sbitany

Walter Adolf De Brouwer

Alexander Cristoff

Provided herein is an implant for delivering a hydrophobic active agent to a target tissue. The implant may include a scaffold defining a first surface and a second surface opposite the first surface, wherein the scaffold is substantially impermeable to a hydrophobic active agent, and a silicone tubing having a wall permeable to the active agent, wherein a first length of the silicone tubing is affixed to the first surface of the scaffold, wherein the two ends of the silicone tubing extend from the first surface, and wherein a path outlined by a second length of the tubing within the first length is circuitous. Also provided is a method of using the implant to locally deliver a hydrophobic active agent to a target tissue, and kits that find use in performing the present method.

Implants for localized drug delivery and methods of use thereof

Provided herein are drug implants comprising enzalutamide for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and enzalutamide disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may be used for the treatment of a proliferative disease of the prostate.

Drug implants containing enzalutamide and methods of use thereof

Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Implantable drug delivery devices for localized drug delivery

Provided herein is an implant for delivering a hydrophobic active agent to a target tissue. The implant may include a scaffold defining a first surface and a second surface opposite the first surface, wherein the scaffold is substantially impermeable to the hydrophobic active agent, and a silicone tubing having a wall permeable to the hydrophobic active agent, wherein a first length of the silicone tubing is affixed to the first surface of the scaffold, wherein two ends of the silicone tubing extend from the first surface, and wherein a path outlined by a second length of the silicone tubing within the first length is circuitous. Also provided is a method of using the implant to locally deliver the hydrophobic active agent to the target tissue, and kits that find use in performing the present method.

Systems, methods, and apparatus are disclosed aggregating at least two of vital signs data, diagnostic test results, medical data, and user parameters into a single medical record. In one example, a method may include periodically receiving vital signs data and/or diagnostic test results performed on a user; periodically receiving medical data in response to a medical examination of the user performed by a health care practitioner; receiving user parameters about the user; aggregating the vital signs data and/or diagnostic test results, the medical data, and the user parameters into a single medical record; associating the single personal medial record with the user; and storing the single personal medial record into a database of personal medical records. Life expectancy can be calculated. Data aggregation can be performed over time for comparison in real time to medical standard values allowing the user to set personal goals towards greater life expectancy.

Systems, methods, and apparatus for personal medical record keeping

Growing community of inventors

Oakland, CA, United States of America

Scott Thomas