Nereus Pharmaceuticals, Inc.

Scott Sherman Mitchell

Kin S Lam

Barbara Christine Potts

Katherine Anne Reed

Ta-Hsiang Chao

Benjamin Nicholson

Jennifer Grodberg

Ginger Tsueng

Ram Rao Manam

Saskia Neuteboom

Cheryl L Billstrom

Donald J White

Venkat Macherla

Katherine A McArthur

Compounds of Formulae I-VI and derivatives thereof having anti-cancer, anti-inflammatory, and anti-microbial properties and to compositions that include one or more of compounds and their derivatives or analogs having anti-cancer, anti-inflammatory and anti-microbial properties are disclosed. Pharmaceutical compositions comprising such compounds and methods of treating cancer, inflammatory conditions, and microbial infections with the disclosed compounds or the disclosed pharmaceutical compositions are also disclosed.

[3.2.0] Heterocyclic compounds and methods of using the same

Compounds of Formula I, commonly referred to as bis-indole pyrroles, including isolated naturally-occurring compounds, synthetic and semi-synthetic derivatives thereof having antimicrobial properties and to antimicrobial compositions that include one or more of bis-indole pyrroles and their derivatives or analogs having antimicrobial properties are disclosed. Pharmaceutical compositions comprising such compounds and methods of treating bacterial infections with the disclosed compounds or the disclosed pharmaceutical compositions are also disclosed.

Bis-indole pyrroles useful as antimicrobials agents

Growing community of inventors

San Carlos, CA, United States of America

Scott Sherman Mitchell