Boston Scientific Scimed, Inc.

Scimed Life Systems, Inc.

Other

Cardiac Pacemakers, Inc.

Medtronic Ireland Manufacturing Unlimited Company

Metavention, Inc.

Boston Scientific Corporation

Scott R. Smith

Scott Raymond Smith

Roger Noel Hastings

David John Sogard

Mark Lynn Jenson

Daniel M Lafontaine

Anthony Ciro Vrba

William Joseph Drasler

Brian J Brown

Anupama Sadasiva

Lance A Monroe

Michael J Pikus

Graig Leonard Kveen

Martin R Willard

Douglas R Saholt

Lixiao Wang

Susan M Shoemaker

Douglas P Killion

Jan Weber

Patrick A Haverkost

Stephen A Griffin

Jonathan A Coe

Leonard B Richardson

Jaydeep Yeshwant Kokate

Jason P Hill

Lex Philip Jansen

Dachuan Yang

Kevin D Edmunds

Sheng-Ping Zhong

Robert L Cassell

James G Hansen

Matthew M Burns

David J Blaeser

Liliana Atanasoska

Robert Warner

Michael N Helmus

Michael J Root

Bobak Robert Azamian

Thomas E Broome

Scott M Hanson

Alan David Eskuri

Scott Bradley Vafai

Steven E Walak

Lloyd K Willard

Joel N Groff

Jeffrey H Vogel

Mark J Whalen

Eric Michael Petersen

Kelly Justin McCrystle

Eric M DoBrava

Joel L Stanslaski

Dave J Sogard

Alain Cornil

William J Drassler

Rajesh Radhakrishnan

Jan D Seppala

John M K Daniel

Kenneth R Larson

Mel R Beulke

Dnyanesh Talpade

Sheng-ping Zhong

Christopher Brian Brodeur

David W Lodin

Joe Koblish

Mourad Rahi

Bruce E Hammer

Gary R Kostur

Gary J Pederson, Jr

Robert J Robinson

Robert L Kaaren

Matthew P Shults

Mishel E Munayyer

Douglas B Molland

Eric M Dobrava

Mark Wilson Ian Webster

Susan A Shoemaker

Diane C Altwies

Michelle T Delizio

Jeffery H Vogel

Alain c/o Scimed Life Systems Inc Cornil

Alan D Eskuri

Kevin Robert Hykes

Rossana Motta

Kathryn Elizabeth Empanger

Kenneth J Malomo

Michael David Perry

Eric Robert Reuland

Victor Kelvin Sun

Kelly Justin Mccrystle

Jonathan Allen Coe

According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) or other tissue are provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves surrounding (e.g., within adventitia of or within perivascular space of) an artery or other blood vessel, such as the common hepatic artery.

Systems and methods for modulating nerves or other tissue

Some embodiments of pacing systems employ wireless electrode assemblies to provide pacing therapy. The wireless electrode assemblies may wirelessly receive energy via an inductive coupling so as to provide electrical stimulation to the surrounding heart tissue. In certain embodiments, the wireless electrode assembly may include one or more biased tines that shift from a first position to a second position to secure the wireless electrode assembly into the inner wall of the heart chamber.

Cardiac stimulation system

A catheter is configured to access a renal artery. A lumen of the catheter's shaft is dimensioned to receive a flexible actuation member which extends between the shaft's proximal and distal ends. The actuation member is moveable within the lumen and subject to elastic deformation, friction, and/or whip along its length. A flexible support member is coupled to a distal end of the actuation member and extendible beyond a distal tip of the shaft. An RF ablation electrode at a distal end of the support member is configured to ablated perivascular renal nerve tissue. A position converter at the distal end of the shaft is configured to convert movement of the actuation member into one or both of controlled rotational and axial movement of the support member and electrode to one of a multiplicity of stable circumferential positions substantially free of elastic deformation, friction, and/or whip impacting actuation member movement.

Precision electrode movement control for renal nerve ablation

According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) or other tissue are provided. Systems, devices and methods for cooling energy delivery members are also provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves surrounding (e.g., within adventitia of or within perivascular space of) an artery or other blood vessel, such as the common hepatic artery.

Therapeutic tissue modulation devices and methods

Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.

Leadless cardiac stimulation systems

Systems and methods for monitoring and performing tissue modulation are disclosed. An example system may include an elongate shaft having a distal end region and a proximal end and having at least one modulation element and one sensing electrode disposed adjacent to the distal end region. The sensing electrode may be used to determine and monitor changes in tissue adjacent to the modulation element.

Device and methods for renal nerve modulation monitoring

A composite biomaterial having a continuous metal sheet with arcuate members that define a first fenestration pattern, and a polymer layer over at least one surface of the continuous metal sheet. The arcuate members elastically stretch to allow the continuous metal sheet to bend in more than one axis without buckling or wrinkling.

Synthetic composite structures

Systems for nerve modulation through the wall of a blood vessel are disclosed. An example system for nerve modulation may include an elongate member extending along a central elongate axis and having a proximal end and a distal end. The elongate member may have a radially expandable member disposed proximate the distal end. A tubular sheath may be cooperatively engaged with the expandable member such that the expandable member is collapsed when in the sheath and can expand when moved distally relative to and past a distal end of the sheath. The expandable member may include a plurality of electrodes and a plurality of spacer struts. Each spacer strut may be configured such that when the self-expanding member is in an expanded state the spacer strut extends out radially further than the electrodes from the central elongate axis.

Off-wall electrode device and methods for nerve modulation

An elongated flexible medical device is inserted into a patient's body via a natural orifice, and advanced through the natural orifice to a location proximate innervated tissue that influences renal sympathetic nerve activity. The medical device can be advanced into a body organ and to a location within the organ proximate the innervated tissue. The organ may comprise an organ of the gastrointestinal tract or urinary tract. The medical device may be advanced through and beyond an access hole in a wall of the organ, and situated at a location proximate the innervated tissue. One or both of imaging and ablation energy is delivered from a distal end of the medical device to the innervated tissue. Innervated renal tissue can be ablated using various forms of energy, including RF energy, ultrasound energy, optical energy, and thermal energy.

Minimally invasive access for renal nerve ablation

Growing community of inventors

Chaska, MN, United States of America

Scott Raymond Smith