Warsaw Orthopedic, Inc.

Scott Mitchell Vickers

Jeffrey L Scifert

Nelson L Scarborough

Jeffrey Mendel Gross

Mirian Gillissen

Didier Billy

Steve Peckham

Jeffrey M Badura

William F McKay

Kathy L Remsen

Jared J Diegmueller

Daniel A Shimko

Rodney Ray Ballard

Christopher M Patterson

Kerem N Kalpakci

Ian Dunkley

Ian R Dunkley

Jason A Rister

A bone implant for enclosing bone material is provided. The bone implant comprises a mesh having an inner surface and an outer surface opposing the inner surface. The inner surface is configured to receive a bone material when the inner surface of the mesh is in an open configuration. A plurality of projections are disposed on or in at least a portion of the inner surface of the mesh. The plurality of projections extend from at least the portion of the inner surface of the mesh and are configured to engage a section of the inner surface of the mesh or a section of the outer surface of the mesh or both sections of the inner and outer surfaces of the mesh in a closed configuration so as to enclose the bone material. A tray, a kit and a method of making the bone implant are also provided.

Bone implant for enclosing bone material

A kit for deploying a bone implant at a surgical site is provided. The kit comprises a first sleeve having an interior surface that defines a channel, and a second sleeve having an outer surface and an inner surface. The inner surface of the second sleeve defines an inner channel. The outer surface of the second sleeve is configured to slidably engage the interior surface of the channel of the first sleeve. A bone implant is also provided comprising a mesh material. The mesh material is disposed in a portion of the channel of the first sleeve or disposed in a portion of the inner channel of the second sleeve or disposed in both the portion of the channel of the first sleeve and the portion of the inner channel of the second sleeve.

Bone implant having a mesh

Provided is an implantable composite which includes a plurality of resorbable ceramic particles with or without a biodegradable polymer. The resorbable ceramic particles can be granules including carbonated hydroxyapatite and tricalcium phosphate in a ratio of 5:95 to 70:30. Some resorbable ceramic particles are granules, which include carbonated hydroxyapatite and &#x3b2; tricalcium phosphate in a ratio of 5:95 to 70:30. The resorbable ceramic particles have a particle size from about 0.4 to about 3.5 mm. The implantable composite is configured to fit at or near a bone defect as an autograft extender to promote bone growth. Methods of using the implantable composite are also provided.

Implantable composite containing carbonated hydroxyapatite

A delivery system comprising an agent and a foldable covering including a first surface disposed with the agent and a second surface connectable with the first surface to intra-operatively dispose the covering in a selected configuration.

Spinal implant system and method

Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided.

Osteoimplant comprising an insoluble fibrous polymer

In certain described embodiments, implantable medical materials comprise a scaffolding material, a liquid organic binder, and entrapped calcium-containing particles. The medical materials can incorporate an osteoinductive factor such as a protein. The scaffolding material can bind the factor. In additional described embodiments, implantable medical materials include an osteoconductive scaffolding material, an incorporated osteoinductive factor, and a biodegradable barrier material effective to delay release of the factor from the scaffolding material. The scaffolding material can bind the factor. Also described a methods for preparing and implanting the described medical materials.

Compositions for treating bone defects

Compositions and methods are provided for preparing an adhesion barrier in the form of a foldable or flexible biodegradable polymer matrix that effectively reduces, prevents or treats adhesions in a patient in need thereof. In one embodiment, the matrix comprises a first porous layer comprising collagen and a second porous layer comprising collagen and dextran, wherein the dextran is loaded in the second layer in an amount of from about 5% to about 90% by weight based on a total weight of the matrix. In some embodiments, the matrix prevents or reduces cell growth into the matrix so as to reduce or prevent adhesions. In some embodiments, the matrix is in a sheet or strip form that can be folded into a tube form.

Multi-layered anti-adhesion device

A spinal implant comprises a plurality of members. At least one element connects the members. An agent is disposed with at least one of the members. The members and the agent are disposable between a configuration for simultaneous delivery to a surgical site and an implant configuration. Systems, spinal constructs, surgical instruments and methods are disclosed.

Described are implantable, malleable medical materials comprising mineral particles, insoluble collagen fibers, and a gel-forming polysaccharide component and/or another added gel-former. The malleable medical materials can be used treat bone or other tissue defects in patients, including in conjunction with biologically active factors such as osteogenic proteins. Also described are methods and materials that can be used to prepare the malleable medical materials.

Growing community of inventors

Hernando, MS, United States of America

Scott Mitchell Vickers