Amgen Inc.

Forsight Vision4, Inc.

Scott M Nunn

Sheldon B Moberg

Mark Dominis Holt

Francisca Tan-Malecki

Ronald Forster

Son C Tran

Lionel Vedrine

Mark Sponsel

Keith Bianchi

Bill Hartsig

Mukund Patel

Ariel Waitz

Ron Forster

An ocular implant system including an ocular implant sized and shaped to be inserted at least partially into an eye; a carrier member with a shell having a central channel extending at least partially through the shell from a proximal end towards a distal end of the shell. A guide sleeve removably attached within at least a first region of the central channel of the shell and defining a proximal port into the central channel that is accessible from the proximal end of the shell. An implant holder removably attached within at least a second region of the central channel of the shell adjacent to a distal end of the guide sleeve and having a pair of graspers adapted to releasably secure the implant at a distal end of the implant holder. Related devices, systems, and/or methods are described.

Ocular implant delivery device and method

An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

Injector and method of assembly

Method of assembling and filling a drug delivery device

An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product, including a granulocyte colony-stimulating factor (G-CSF). The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

An injector () may include a container () having a wall () with an interior surface () and a seal assembly () with an interior surface (), the interior surfaces () of the wall () and the seal assembly () defining a closed sterile reservoir () filled with a drug product. The injector () may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle () having a point () disposed only partially through the seal assembly () in a storage state, and disposed through the interior surface () of the seal assembly () into the sterile reservoir () in a delivery state. Further, the injection may include an actuator () that is adapted to move the container needle from the storage state to the delivery state.

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San Mateo, CA, United States of America

Scott M Nunn