Agbiome, Inc.

Novartis Finance Corporation

Ciba-geigy Corporation

Syngenta Participations Ag

Novartis Ag

Novartis Corporation

Certis Usa, LLC

Scott Joseph Uknes

Philip E Hammer

Janice C Jones

John A Ryals

Michael G Koziel

Eric Russell Ward

Leslie B Friedrich

Eric R Ward

James Joseph Beck

Terrence Patrick Delaney

Daniel John Tomso

Rebecca E Thayer

Jessica Parks

Thomas Schupp

Stephen T Lam

Vadim Beilinson

Thomas D Gaffney

Dwight Steven Hill

Peter Bernard Heifetz

James M Ligon

Christian T Harms

Kelly S Smith

Edouard Guillaume Lebel

Sandy Volrath

Henry-York Steiner

Kay A Lawton

Jeffrey R Stinson

Robert M Goodman

Helmut Kessmann

Danny C Alexander

Christoph Sperisen

Mary B Moyer

George B Payne

Jean-Marc Neuhaus

John H Duesing

Frederich Meins, Jr

Alice Montoya, Deceased

Shericca C Williams

Klaus Maleck

Kristianna Baldwin Weymann

Amy Elizabeth Shekita

Gertrude Knauf-Beiter

Wilhelm Ruess

Ruth Beatrice Kung

Michael Oostendorp

Daniel Murray Ellis

Antonio Molina-Fernandez

Bernardus T Vernooij

Michelle Denise Hunt

Pieter Vos

Taco Peter Jesse

Methods for improving the ability of a population of biological agents to compete and survive in a field setting are provided. By improving the population of biological agents, the modified population of agents is able to grow, compete with other microbial strains and fungi, and provide protection for plants from pathogens. In particular, modified biological agents and modified populations of such agents that are herbicide tolerant or resistant are selected or engineered. In this manner, the protection from disease-causing agents is enhanced. Such modified populations of biological agents can be added to soils to prevent fungal pathogens and the diseases they cause promoting plant growth. Therefore, the present invention is useful for enhancing the competitiveness of modified biological agents particularly over other microbial agents which are not herbicide resistant. Compositions of the invention include selected or engineered herbicide resistant biological agents and modified populations of biocontrol agents. These modified biological agents can be used as an inoculant or as a seed coating for plants and seeds.

Modified biological control agents and their uses

Compositions and methods for isolating new variants of known gene sequences are provided. The methods find use in identifying variants, particularly homologs, in complex mixtures. Compositions comprise hybridization baits that hybridize to gene families of interest, particularly agricultural interest, in order to selectively enrich the polynucleotides of interest from complex mixtures. Bait sequences may be specific for a number of genes from distinct gene families of interest and may be designed to cover each gene of interest by at least 2-fold. Thus methods disclosed herein are drawn to an oligonucleotide hybridization gene capture approach for identification of new genes of interest from environmental samples. This approach bypasses the need for labor-intensive microbial strain isolation, permits simultaneous discovery of genes from multiple gene families of interest, and increases the potential to discover genes from low-abundance and unculturable organisms present in complex mixtures of environmental microbes.

High throughput discovery of new genes from complex mixtures of environmental microbes

Methods for improving the ability of a population of biological agents to compete and survive in a field setting are provided. The modified population of agents is able to grow, compete with other microbial strains and fungi, and provide protection for plants from pathogens. Modified biological agents and modified populations of such agents that are herbicide tolerant or resistant are selected or engineered. In this manner, the protection from disease-causing agents is enhanced. Such modified populations can be added to soils to prevent fungal pathogens and associated diseases, promoting plant growth. The present invention is useful for enhancing the competitiveness of modified biological agents particularly over other microbial agents which are not herbicide resistant. Compositions include selected or engineered herbicide resistant biological agents and modified populations of biocontrol agents. These modified biological agents can be used as an inoculant or as a seed coating for plants and seeds.

Methods for improving the ability of a population of biological agents to compete and survive in a field setting are provided. The improved, modified population of agents is able to grow, compete with other microbial strains and fungi, and provide protection for plants from pathogens. Modified biological agents and modified populations of such agents that are herbicide tolerant or resistant are selected or engineered. In this manner, the protection from disease-causing agents is enhanced. Such modified populations can be added to soils to prevent fungal pathogens and the associated diseases thereby promoting plant growth. The present invention is useful for enhancing the competitiveness of modified biological agents particularly over other microbial agents which are not herbicide resistant. Disclosed compositions include selected or engineered herbicide resistant biological agents and modified populations of biocontrol agents. These modified biological agents can be used as an inoculant or seed coating for plants and seeds.

Methods of growing plants using modified biological control agents

Growing community of inventors

Apex, NC, United States of America

Scott Joseph Uknes